Pharmacology (metabolic) PhD Projects, Programmes & Scholarships

We have 14 Pharmacology (metabolic) PhD Projects, Programmes & Scholarships

The role of extracellular vesicles in signalling between cardiovascular cell types in metabolic diseases and in cardioprotective therapies

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

We are to understand how EVs induce and affect cardiovascular diseases. To this end, we investigate its changes in disease models of the cardiovascular system and in its comorbidities, e.g., metabolic diseases. Read more

Supervisor: Dr Z Giricz

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Investigation of myocardial ischemic adaptation in the presence of comorbidity factors on in vitro cell culture models

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

Metabolic derangements, such as obesity or diabetes, are major risk factors of cardiovascular diseases. Read more

Supervisor: Dr A Görbe

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Identification of novel inflammatory mechanisms as potential therapeutic targets in cardiovascular and metabolic diseases

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

The prognosis of chronic heart failure resulting from a heart attack is very poor, even with modern therapeutic devices and drugs, about half of the patients die within 5 years of diagnosis. Read more

Supervisor: Dr Z Varga

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Understanding the molecular mechanisms of thrombosis and haemostasis

University of Reading Department of Biomedical Sciences

Project Overview: . The risk of heart attack or stroke is elevated in obesity and in people with metabolic disorders such as diabetes. Read more

Supervisors: Dr C.E. Hughes, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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The clinical and therapeutic impact of disialoganglioside GD2 and its synthases on breast cancer

Cardiff University Cardiff School of Medicine

Disialoganglioside GD2 is a plasma membrane member of the large glycosphingolipid family which involves a hydrophobic ceramide bound to a hydrophilic sialic acid-containing glycan chain. Read more

Supervisor: Prof WG Jiang

24 May 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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Neurovascular coupling in cerebral hypoperfusion

The University of Manchester Faculty of Biology, Medicine and Health

There are almost a million people living with dementia in the UK. Most of these cases comprise Alzheimer’s Disease (AD), vascular dementia (VaD) or, as is increasingly recognised, a mixed picture phenotype with evidence of the two conditions co-existent in the same patient. Read more

Supervisors: Dr H Pritchard, Dr A Greenstein, Dr I Schiessl, Prof S Allan

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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MScR: Involvement of astrocytes in neurological manifestations of Long COVID syndrome

University of Bristol School of Physiology, Pharmacology & Neuroscience

A significant fraction of patients affected by Long COVID, long-term consequences following acute SARS-CoV-2 infection, suffer from mental fatigue and cognitive deficits (1-3). Read more

Supervisor: Prof A Teschemacher

Year round applications PhD Research Project Self-Funded PhD Students Only

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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics

Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more

Supervisor: Dr RB Burton

1 July 2024 PhD Research Project Self-Funded PhD Students Only

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Evaluating the therapeutic potential of leptin-based hexamers in neurodegenerative disease

University of Dundee School of Medicine

Translation of basic research into Alzheimer’s disease (AD) therapies is hindered by our inability to turn promising lab results into drugs that can be taken by patients. Read more

Supervisors: Prof J Harvey, Dr C Henstridge, Dr A McNeilly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Queen’s University Belfast School of Pharmacy

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Supervisors: Dr I Tikhonova, Dr B Plouffe

Year round applications PhD Research Project Self-Funded PhD Students Only

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Inducing ferroptotic death to kill cancer cells

The University of Manchester Faculty of Biology, Medicine and Health

Ferroptosis is an iron-dependent form of regulated necrotic cell death triggered by oxidative degradation of lipids in membrane bilayers and subsequent irreparable damages to the plasma membrane (1). Read more

Supervisors: Dr C Tournier, Dr K Finegan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using CRISPR in iPS cells to modify platelet function

University of Reading Department of Biomedical Sciences

Project Overview. Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus. Read more

Supervisor: Dr C.E. Hughes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-Navigating Nanocarriers for Intracellular Protein Delivery

Queen’s University Belfast School of Pharmacy

Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more

Supervisor: Dr W Al-Jamal

Year round applications PhD Research Project Self-Funded PhD Students Only

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Biological role of neuropeptides and their receptors

University of Reading School of Pharmacy

Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well. Read more

Supervisor: Dr L Lander

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 14 Pharmacology (metabolic) PhD Projects, Programmes & Scholarships

Pharmacology (metabolic) PhD Projects, Programmes & Scholarships

We have 14 Pharmacology (metabolic) PhD Projects, Programmes & Scholarships

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