Pharmacology (molecular modelling) PhD Projects, Programmes & Scholarships

We have 9 Pharmacology (molecular modelling) PhD Projects, Programmes & Scholarships

Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Queen’s University Belfast School of Pharmacy

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Supervisors: Dr I Tikhonova, Dr B Plouffe

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Supervisors: Dr M Young, Dr J Parker

Year round applications PhD Research Project Self-Funded PhD Students Only

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Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Supervisor: Dr T You

1 August 2024 PhD Research Project Self-Funded PhD Students Only

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Network-based predictive modelling of cardiovascular disease risk

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The risk of cardiovascular disease (CVD) is orchestrated by multiple factors. QRISK models (currently QRISK3) have been used in the UK to estimate CVD risk within the next 10 years for individuals without CVD. Read more

Supervisor: Dr T You

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cardiac Harmony: Modelling Heart Beats with Stem Cells and Code

University of Liverpool Institute of Life Course and Medical Sciences

Despite significant advancements in cardiac research, heart disease remains a leading cause of mortality globally. Unexpected cardiac events can occur even in young, fit individuals engaged in routine activities. Read more

Supervisors: Prof R Barrett-Jolley, Dr R Oldershaw

Year round applications PhD Research Project Self-Funded PhD Students Only

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Funded PhD - Determining the genetic and circadian basis of bipolar disorder

University of Bristol School of Physiology, Pharmacology & Neuroscience

This project will be part of the University of Bristol - University of Kent Cotutelle Programme. It will be jointly supervised by Prof James Hodge (http://www.bristol.ac.uk/phys-pharm-neuro/people-new/hodge/) and Dr Alice French at the University of Bristol, and by Prof Gurprit Lall at University of Kent. Read more

Supervisors: Prof J Hodge, Dr AF French

12 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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SLS SF3: PhD in Pharmacological intervention of ion channels for the treatment of cardiac disease

University of Westminster School of Life Sciences

Within our lab we study human ion channels, mainly potassium channels, that contain genetic mutations which lead to disease states. Read more

Supervisors: Dr KP Cunningham, Dr S Getting, Dr DG Gaze

17 May 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating the links between β-amyloid, osteoporosis and frailty in Alzheimer’s disease

Queen Mary University of London Institute of Dentistry

Background. Individuals with Alzheimer’s disease are more likely to suffer from osteoporosis (the loss of bone mass and strength) than age-matched individuals1, significantly contributing to the frailty associated with dementia. Read more

Supervisors: Dr S McArthur, Dr SCF Rawlinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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The use of Drosophila melanogaster to identify novel therapeutic agents for Alzheimer’s disease

University of Nottingham School of Life Sciences

Since 2003, our understanding of the causes of Alzheimer’s disease (AD) have improved considerably, however, in that time only one new drug treatment has been approved. Read more

Supervisors: Dr M Georgiou, Dr Z Zhu

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 9 Pharmacology (molecular modelling) PhD Projects, Programmes & Scholarships

Pharmacology (molecular modelling) PhD Projects, Programmes & Scholarships

We have 9 Pharmacology (molecular modelling) PhD Projects, Programmes & Scholarships

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