Pharmacology (plasma) PhD Projects, Programmes & Scholarships

We have 10 Pharmacology (plasma) PhD Projects, Programmes & Scholarships

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Supervisors: Dr M Young, Dr J Parker

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of extracellular vesicles in signalling between cardiovascular cell types in metabolic diseases and in cardioprotective therapies

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

We are to understand how EVs induce and affect cardiovascular diseases. To this end, we investigate its changes in disease models of the cardiovascular system and in its comorbidities, e.g., metabolic diseases. Read more

Supervisor: Dr Z Giricz

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Investigation of short-term effects of colchicine on blood proteins using proteomics

University of Dundee School of Medicine

The anti-inflammatory medication colchicine has been shown to significantly improve cardiovascular outcomes post heart attack and in chronic heart disease patient groups, suggesting it may be a suitable candidate for repurposing in cardiovascular diseases. Read more

Supervisors: Prof G Rena, Dr I Mordi, Prof C Lang

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Pharmacological and toxicological effects of pollutants on the cardiovascular system

Charles University Faculty of Pharmacy

Faculty of Pharmacy, Charles University, Department of Pharmacology and Toxicology. The majority of the world's population lives in medium or large cities where human activities (industry, transport, etc.) have a direct impact on the production of pollutants. Read more

Supervisor: Prof P Mladěnka

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Targeting Ras palmitoylation for the treatment of cancer

University of Dundee School of Medicine

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Supervisor: Dr N Fraser

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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PBPK modelling of disease-drug interactions using transporter and enzyme biomarker data

The University of Manchester Faculty of Biology, Medicine and Health

Precision dosing strategies require accounting for between-patient variability in pharmacokinetics. Read more

Supervisors: Dr A Galetin, Dr Daniel Scotcher, Prof A Rostami

Year round applications PhD Research Project Self-Funded PhD Students Only

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Microneedle delivery systems for minimally-invasive patient diagnosis/monitoring

Queen’s University Belfast School of Pharmacy

In this project, a novel type of integrated system will be investigated that will by-pass the skin barrier. On its surface will be multiple microscopic needles that pierce the skin without causing any pain – the sensation is said to feel like a cat’s tongue or sharkskin. Read more

Supervisor: Prof R Donnelly

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanisms underlying the anti-atherogenic actions of natural products

Cardiff University Cardiff School of Biosciences

Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for most deaths in the western world with mortality increasing at a marked rate in developing. Read more

Supervisors: Dr D Ramji, Dr T Hughes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Inducing ferroptotic death to kill cancer cells

The University of Manchester Faculty of Biology, Medicine and Health

Ferroptosis is an iron-dependent form of regulated necrotic cell death triggered by oxidative degradation of lipids in membrane bilayers and subsequent irreparable damages to the plasma membrane (1). Read more

Supervisors: Dr C Tournier, Dr K Finegan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Interaction between innate immune activation and endothelial cells, linked to adverse cardiovascular events

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The complement system is a key component of the immune response. Maintaining a balance between activation and inhibition of the complement system is key to preserving tissue homeostasis and enabling immune surveillance. Read more

Supervisors: Dr N Liptrott, Dr R Rainbow, Prof C Dart

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 10 Pharmacology (plasma) PhD Projects, Programmes & Scholarships

Pharmacology (plasma) PhD Projects, Programmes & Scholarships

We have 10 Pharmacology (plasma) PhD Projects, Programmes & Scholarships

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