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We have 30 Pharmacology (studentship) PhD Projects, Programmes & Scholarships

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Pharmacology (studentship) PhD Projects, Programmes & Scholarships

We have 30 Pharmacology (studentship) PhD Projects, Programmes & Scholarships

Dissecting behaviourally relevant feedback microcircuits in the brain

Interactions between distinct neural circuits in the brain help in sensory-guided perceptual decisions. We have recently reported that task/context-switching behaviour is dependent upon specific populations of neurons in the frontal cortex which encode and convey rule-related information (Banerjee et al. Read more

Investigating how dormant senescent cells can drive drug-resistance following chemotherapy

Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more

Virus antigenic evolution under immune pressure

About the Project. The persistent evasion of COVID-19 from vaccines and monoclonal antibody therapeutics underscores the critical need to comprehend how endemic and zoonotic viruses evolve to counter antibody-mediated immune responses. Read more

Neurovascular coupling in cerebral hypoperfusion

There are almost a million people living with dementia in the UK. Most of these cases comprise Alzheimer’s Disease (AD), vascular dementia (VaD) or, as is increasingly recognised, a mixed picture phenotype with evidence of the two conditions co-existent in the same patient. Read more

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Investigation of short-term effects of colchicine on blood proteins using proteomics

The anti-inflammatory medication colchicine has been shown to significantly improve cardiovascular outcomes post heart attack and in chronic heart disease patient groups, suggesting it may be a suitable candidate for repurposing in cardiovascular diseases. Read more

Using chemical-genetics to inhibit and characterise “undruggable” enzymes

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

Using lipid nano-particles to study G-protein-coupled receptors (GPCRs).

This exciting PhD project in the laboratory of Professor Mark Wheatley, Professor of Biochemical Pharmacology is a joint PhD between Coventry University and Stellenbosch University with the student being registered for a PhD at both universities. Read more

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