Pathology PhD Research Projects PhD Projects, Programmes & Scholarships in the UK

We have 98 Pathology PhD Research Projects PhD Projects, Programmes & Scholarships in the UK

Immune-dysregulation in chronic inflammatory muco-cutaneous disorders

Aberdeen University School of Medicine, Medical Sciences & Nutrition

This exciting PhD project provides a rare opportunity to discover novel mechanisms of immune-dysregulation in under-researched but clinically important… Read more

Supervisors: Prof K Hijazi, Dr R Abu Eid, Prof D J Blackbourn

18 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Significance of acari as location and time makers of buried corpses and mass graves

University of Reading School of Biological Sciences

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Supervisor: Dr M A Perotti

21 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The University of Manchester Faculty of Biology, Medicine and Health

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

Supervisors: Dr MM Mennon, Prof MH Buch

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Health and education outcomes of children with Sickle Cell Disease in England

Great Ormond Street Hospital for Children NHS Trust GOSH BRC Applied Child Health Informatics Theme (Non-Clinical) PhD Studentships

SCD is a serious, life-long condition that can cause anaemia, increased infection risk, and pain.1 Around 300 babies are born with SCD annually in the UK. Read more

Supervisors: Dr R Knowles, Prof P Hardelid

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Systemic infections accelerate tau spreading by promoting glial activation

University of Southampton School of Biological Sciences

Alzheimer’s disease (AD) is a neurodegenerative disease, with a complex biology. In this PhD project, we aim to explore the cellular and molecular mechanisms underlying tau pathology. Read more

Supervisor: Prof J Teeling

17 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute

Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more

Supervisors: Dr M Secrier, Dr L Cottone

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating mechanisms of extra-cellular matrix remodelling and fibrosis in the gastrointestinal tract

University of Dundee School of Medicine

Inflammatory bowel diseases, such as Crohn's disease, are increasing in prevalence globally. These are caused by chronic inflammation in the gut, there is no cure and medications are not effective for all. Read more

Supervisor: Dr M Mclean

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Leveraging novel automated diagnostic pathways with augmented precision medicine approaches for the early detection and risk stratification of liver disease

University of Dundee School of Medicine

Liver disease represents one of the fastest-growing causes of morbidity and mortality in the world. The principle aetiological variants are contained within the new nomenclature of steatotic liver disease (SLD). Read more

Supervisors: Dr P Brennan, Prof J F Dillon, Dr M Al-Khairalla

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Advancing Mass Spectrometry Tools for Endotyping Chronic Respiratory Diseases

University of Dundee School of Medicine

Chronic respiratory diseases, including COPD, asthma, and bronchiectasis, pose significant challenges in management due to their diverse clinical manifestations. Read more

Supervisors: Dr J Huang, Prof J Chalmers

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Exploring cardio-renal-metabolic interactions in patients with heart failure

University of Dundee School of Medicine

Recent years have highlighted the connections and shared pathophysiology between heart failure, renal impairment, diabetes and obesity, particularly with the evidence of benefit in all of these areas with SGLT2 inhibitors and GLP1-receptor agonists. Read more

Supervisor: Dr I Mordi

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigation of short-term effects of colchicine on blood proteins using proteomics

University of Dundee School of Medicine

The anti-inflammatory medication colchicine has been shown to significantly improve cardiovascular outcomes post heart attack and in chronic heart disease patient groups, suggesting it may be a suitable candidate for repurposing in cardiovascular diseases. Read more

Supervisors: Prof G Rena, Dr I Mordi, Prof C Lang

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Lessening Health Inequalities in Type 2 Diabetes Through Innovative Drug Repurposing

University of Dundee School of Medicine

Most older type 2 diabetes (T2D) drugs were developed through pre-clinical studies and then trials that model T2D as it is experienced by older white people (1). Read more

Supervisor: Prof G Rena

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Learning and Memory in the response to recurrent hypoglycaemia in diabetes

University of Dundee School of Medicine

Recurrent hypoglycaemia has both acute and chronic consequences and is greatly feared by people with type 1 diabetes. Work from our laboratory over the last few years has revealed that the brain adaptation to recurrent hypoglycaemia in type 1 diabetes represents a specialised form of memory called habituation. Read more

Supervisors: Prof R McCrimmon, Dr A McNeilly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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The inflammatory response to recurrent hypoglycaemia in diabetes

University of Dundee School of Medicine

Recurrent hypoglycaemia has both acute and chronic consequences and is greatly feared by people with type 1 diabetes. Read more

Supervisor: Prof R McCrimmon

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Vascularisation of tumour organoids for mechanistic and drug development

University of Dundee School of Medicine

Gliomas such as are the most common form of brain tumour, a subset Glioblastoma (GBM) are devastating adult brain cancer with high rates of recurrence and treatment resistance. Read more

Supervisors: Dr C Murdoch, Dr S Banerjee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Identifying secreted biomarkers in brain cancer

University of Dundee School of Medicine

Stage IV brain cancer or glioblastoma (GBM) poses a major challenge with only 5 FDA approved chemotherapeutic drugs available for treatment. Read more

Supervisor: Dr S Banerjee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating how dormant senescent cells can drive drug-resistance following chemotherapy

University of Dundee School of Medicine

Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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The Holistic Microbiome in Health and Disease: Linking the Oral, Gut and Respiratory Microbiomes

University of Dundee School of Medicine

The human gut microbiome is recognised as a major determinant of health and disease. Studies to date, including those of the international Human Microbiome Project, have largely focused on individual body sites such as nose or mouth or faeces. Read more

Supervisors: Dr R Hansen, Dr A Dicker, Dr C Mowat

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Immune regulation of lung repair, and long-term consequences of infection

University of Edinburgh School of Biological Sciences

This project is one of 14 four year PhD Studentships funded by Medical Research Scotland (MRS) (https://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and External Partner Organisation (EPO). Read more

Supervisors: Prof G Perona-Wright, Dr S Jenkins

14 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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The role of extracellular vesicles and intercellular signalling in inherited kidney cancer

Cardiff University Cardiff School of Medicine

This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£60,000 total). Read more

Supervisor: Dr E Dunlop

31 May 2024 PhD Research Project Self-Funded PhD Students Only

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Leveraging Functional Genomics to Understand Mitonuclear Combinations in Leber Hereditary Optic Neuropathy (Ref: FFS24/HLS/APP/WINTER)

Northumbria University Faculty of Health and Life Sciences

Mitochondria are small structures present in every cell of our body, which convert the food we eat into an energy source that cells can use. Read more

Supervisors: Dr M Winter, Prof M Lako, Dr G Hilgen

25 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating local invasion in primary and secondary brain tumours

University of Liverpool Department of Molecular and Clinical Cancer Medicine

Brain tumours are highly invasive and carry a poor prognosis. Secondary brain tumours or brain metastases (BM) are the most common tumours found in the brain affecting up to one third of patients with solid organ cancer. Read more

Supervisor: Dr RZ Zakaria

2 December 2024 PhD Research Project Self-Funded PhD Students Only

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Investigations into the protective actions of CBD in the early synaptic deficits in dementia.

University of Dundee School of Medicine

Accumulation of hyper-phosphorylated tau is a key event in Alzheimer’s disease (AD). Aberrant changes in tau cause synaptic abnormalities and cognitive deficits in early AD. Read more

Supervisor: Prof J Harvey

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Fertility preservation of male childhood cancer patients

University of Dundee School of Medicine

Every day, around five children receive a diagnosis of cancer in the United Kingdom, with boys slightly more frequently than girls. Read more

Supervisors: Dr F Lopes, Prof R Mitchell

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Examining the dysfunction of DNA damage repair in synucleinopathies

University of Dundee School of Medicine

DNA damage is an emerging stressor implicated in the pathogenesis of neurodegenerative diseases. Our recent research within post-mortem dementia with Lewy body brain tissue has highlighted the dysregulation of several DNA damage repair pathways, alongside the occurrence of a novel nuclear alpha-synuclein pathology. Read more

Supervisor: Dr D Koss

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating Lysosomal Dysfunction in Ageing and Neurodegeneration

University of Dundee School of Medicine

Lysosomes are key cellular organelles that degrade and recycle macromolecules, act as signalling hubs and are implicated in many diseases including Parkinson’s disease (PD) and Alzheimer’s dementia (AD) where old age is a major risk factor. Read more

Supervisor: Dr E Sammler

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Characterisation of novel therapeutic approaches against invasive breast cancer

University of Dundee School of Medicine

Breast cancer is the most common cancer and the leading cause of death from cancer in women worldwide. Read more

Supervisor: Dr L de la Vega

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Validation of novel combination treatments in lung cancer

University of Dundee School of Medicine

Lung cancer is the leading cause of cancer-related deaths and the most common cancer in men and the 2nd most common cancer in women worldwide. Read more

Supervisor: Dr L de la Vega

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating the genetic determinants of ultra-complex telomere fusion

Cardiff University Cardiff School of Medicine

We are seeking a motivated molecular biologist to study the mechanisms by which telomere dysfunction impacts cancer genomes. Read more

Supervisor: Prof D Baird

3 May 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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Study of early pathological changes in calcified cartilage in osteoarthritis and alkaptonuria

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

We are seeking a motivated individual to work on this exciting project investigating the role that the calcified cartilage has in rare and common joint osteoarthritis, using novel approaches such as gene silencing and establishment of a 3D chondrocyte cell culture model. Read more

Supervisor: Dr JH Hughes

10 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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We have 98 Pathology PhD Research Projects PhD Projects, Programmes & Scholarships in the UK

Pathology PhD Research Projects PhD Projects, Programmes & Scholarships in the UK

We have 98 Pathology PhD Research Projects PhD Projects, Programmes & Scholarships in the UK

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