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We have 15 Pathology (development studies) PhD Projects, Programmes & Scholarships

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Pathology (development studies) PhD Projects, Programmes & Scholarships

We have 15 Pathology (development studies) PhD Projects, Programmes & Scholarships

An investigation on the association of high risk human papillomavirus (HPV) types with colonic adenomata and adenocarcinomas: a UK population based study

This PhD studentship invites application for a study “investigating the association between high risk human papillomavirus (HPV) types and colonic adenomata and adenocarcinomas in a UK population”.  Colorectal cancer (CRC) is an important public health problem worldwide occupying most frequent causes of cancer-related mortality. Read more

Clinical Significance and Diagnostic Accuracy of Special Tests in Rotator Cuff Related Shoulder Pain

Special tests are typically used to assist in the diagnostic process by implicating specific tissue structures that are either dysfunctional, pathological, or lack structural integrity, confirming the findings from the physical assessment and providing a tentative diagnosis (Magee, 2014). Read more

Translating biomarkers towards clinical trial application in osteoarthritis

Stipend. Standard Research Council London Rate + Tuition Fees (Home rate) for 3 years. A consumables budget is also provided. Applications are invited for a 3-year PhD studentship based in the Centre for Inflammatory Disease, Department of Immunology & Inflammation at Imperial College London. Read more

Normative modelling of resting-state EEG across the lifespan for application in the early diagnosis of neurodegenerative disorders including Alzheimer’s disease

With a rapidly aging human population worldwide, neurodegenerative diseases represent a pressing medical and societal concern. Given the increase in life expectancy, dementia is expected to affect almost 152 million people by 2050 (Alzheimer’s Disease International, 2018). Read more

Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Investigation of the extracellular matrix as a regulator of Parkinson’s progression

  Research Group: Chemistry and Biosciences
Parkinson’s is the 2nd most common neurodegenerative disease, affecting around 1 in 20 people aged over 65. In the UK, the number of affected people is set to rise by 50% over the next 50 years due to ageing populations. Read more

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

  Research Group: Chemistry and Biosciences
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more

Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more
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