Pathology (environment) PhD Projects, Programmes & Scholarships

We have 14 Pathology (environment) PhD Projects, Programmes & Scholarships

Control of bone shape and function by the extracellular matrix Fibrillin-1

University of Liverpool Institute of Life Course and Medical Sciences

Bones are tightly regulated structures that remodel their structure to adapt to changes in their mechanical environment. With ageing, this mechanical response is often dampened, leading to bone loss and weakness. Read more

Supervisor: Dr B Poulet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of the extracellular matrix as a regulator of Parkinson’s progression

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Parkinson’s is the 2nd most common neurodegenerative disease, affecting around 1 in 20 people aged over 65. In the UK, the number of affected people is set to rise by 50% over the next 50 years due to ageing populations. Read more

Supervisor: Dr SM Dickens

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of new molecular therapies to treat motor neuron disease (MND)

Macquarie University Centre for MND Research

The battle against Motor Neuron Disease (MND) is entering an exciting phase with the development of gene therapies aimed at reducing pathogenic proteins. Read more

Supervisors: Assoc Prof AL Lee, Assoc Prof MM Morsch

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Immune regulation of lung repair, and long-term consequences of infection

University of Edinburgh School of Biological Sciences

This project is one of 14 four year PhD Studentships funded by Medical Research Scotland (MRS) (https://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and External Partner Organisation (EPO). Read more

Supervisors: Prof G Perona-Wright, Dr S Jenkins

14 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Significance of acari as location and time makers of buried corpses and mass graves

University of Reading School of Biological Sciences

Project Overview. . Read more

Supervisor: Dr M A Perotti

21 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute

Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more

Supervisors: Dr M Secrier, Dr L Cottone

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Study of early pathological changes in calcified cartilage in osteoarthritis and alkaptonuria

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

We are seeking a motivated individual to work on this exciting project investigating the role that the calcified cartilage has in rare and common joint osteoarthritis, using novel approaches such as gene silencing and establishment of a 3D chondrocyte cell culture model. Read more

Supervisor: Dr JH Hughes

10 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating the neuro-stromal-immune interactions in inflammageing and osteoarthritis.

University of Greenwich School of Pharmacy (Medway Campus)

Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) including osteoarthritis. Age-associated chronic low-grade inflammation (inflammageing) is a hallmark of osteoarthritis. Read more

Supervisor: Dr S Ashraf

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Supervisors: Dr M Hussain, Dr C Willis, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Supervisors: Dr M Hussain, Dr M Katsikogianni, Dr N Javid

Year round applications PhD Research Project Self-Funded PhD Students Only

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Beat-to-beat modulation of Calcium-induced Calcium release in cardiac muscle

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Contraction in the heart is well known to be dependent on a transient rise in intracellular calcium concentration. Read more

Supervisors: Dr M Hussain, Dr J Muller, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Antisense technologies as potential treatments for Cushing’s disease

University of Sheffield School of Medicine and Population Health

Cushing’s disease is a devastating condition caused by a pituitary corticotroph tumour that over-expresses the proopiomelanocortin gene (POMC) and secretes high levels of ACTH. Read more

Supervisor: Dr E H Kemp

Year round applications PhD Research Project Self-Funded PhD Students Only

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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School

Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more

Supervisors: Dr J Min, Dr E Hannon, Prof J MIll, Dr GL Leyden

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Understanding the molecular mechanisms of thrombosis and haemostasis

University of Reading Department of Biomedical Sciences

Project Overview: . The risk of heart attack or stroke is elevated in obesity and in people with metabolic disorders such as diabetes. Read more

Supervisors: Dr C.E. Hughes, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 14 Pathology (environment) PhD Projects, Programmes & Scholarships

Pathology (environment) PhD Projects, Programmes & Scholarships

We have 14 Pathology (environment) PhD Projects, Programmes & Scholarships

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