Cell Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Manchester

We have 37 Cell Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Manchester

What is the interrelationship between cell mitosis and cell polarity during apical-basal polarisation of epithelial organs?

The University of Manchester Faculty of Biology, Medicine and Health

My group strives to uncover how mechanics and biochemical signalling work together to shape epithelial organs during development. Read more

Supervisors: Dr C.B Buckley, Dr S Woolner

Year round applications PhD Research Project Self-Funded PhD Students Only

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Defining the mechanistic basis of Aspergillus fumigatus and Non-tuberculous mycobacteria coinfection

The University of Manchester Faculty of Biology, Medicine and Health

Respiratory infections caused by bacteria, fungi and viruses are a global cause of death according to the WHO. Respiratory coinfections are on the rise and in general linked with poor patient outcomes. Read more

Supervisors: Dr S Gago, Dr CK Kosmidis, Prof L Tabernero

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cell-matrix interface engineering for regenerative medicine applications and disease modelling

The University of Manchester Faculty of Biology, Medicine and Health

Dr. Mahetab Amer is seeking motivated students with backgrounds in tissue engineering, cell biology, materials science, or related fields to join her dynamic, multidisciplinary research group at the Division of Cell Matrix Biology and Regenerative Medicine, University of Manchester. Read more

Supervisor: Dr M.A Amer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cell signalling and gene expression dynamics in Drosophila

The University of Manchester Faculty of Biology, Medicine and Health

During Drosophila development, cell signalling and gene expression are regulated in space and time to allow the correct cell fate decisions. Read more

Supervisor: Prof H Ashe

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of nuclear localisation of adhesion proteins in tumour growth and invasion

The University of Manchester Faculty of Biology, Medicine and Health

Overview. This project seeks to understand how tumour growth and invasion are controlled by the localisation of certain proteins in cancer cells. Read more

Supervisors: Dr AB Byron, Dr K Finegan, Dr C Tournier

Year round applications PhD Research Project Self-Funded PhD Students Only

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Driving phenotypic plasticity and metastasis in small cell lung cancer

The University of Manchester Faculty of Biology, Medicine and Health

Small cell lung cancer (SCLC) is an aggressive malignancy with poor prognosis. Underlying this aggressiveness is intra-tumoural heterogeneity driven by phenotypic plasticity wherein tumour cells transition from a neuroendocrine (NE) to a non-neuroendocrine (non-NE) phenotype. Read more

Supervisors: Prof A Malliri, Dr K Simpson, Prof C Dive

Year round applications PhD Research Project Self-Funded PhD Students Only

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Diagnostics for FMF patients and carrier survival in pandemics

The University of Manchester Faculty of Biology, Medicine and Health

Background. Familial Mediterranean Fever (FMF) is a rare inherited genetic disease where patients acquire a mutation on the pyrin gene leading to excessive inflammasome activation and excessive inflammation. Read more

Supervisors: Dr P Arkwright, Dr G Lopez-Castejon, Dr J Cavet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating WSB-1 as a prognostic marker and therapeutic target in urogenital cancers

The University of Manchester Faculty of Biology, Medicine and Health

Prostate cancer (PCa) is the commonest cancer diagnosed in men, with 5-year survival rates of 60% in those with advanced disease. Read more

Supervisors: Dr IP Monteiro dos Santos Pires, Prof AC Choudhury

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identifying critical pathways regulating autoimmunity in immuno-oncology and arthritis patients. Short title: IPADS (Immune PAthways for Drug Side-effects)

The University of Manchester Faculty of Biology, Medicine and Health

Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies (inc. Read more

Supervisors: Dr S Viatte, Prof A Barton, Mr P Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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New strategies to cryopreserve cell-based therapies

The University of Manchester Department of Chemistry

In the past decade, cell-based therapies have emerged to transform the treatment of disease, particularly cancer. Whilst potent, these therapies are challenging to deliver in practise as must be stored frozen (cryopreserved). Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Defining the molecular mechanisms of leukaemia chemotherapies

The University of Manchester Faculty of Biology, Medicine and Health

Chemotherapies are usually the backbone of cancer treatment for either curative or palliative patient care. Multiple therapies can be used for the same disease, with the choice of drug dependent on parameters such as the patient’s age and fitness. Read more

Supervisors: Dr JK Knight, Dr K Batta, Dr D Wiseman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cell-biological mechanisms mediating primary cilium mediated interpretation of Shh signalling during vertebrate neuronal differentiation

The University of Manchester Faculty of Biology, Medicine and Health

Newborn neurons undergo extensive morphological changes as they polarise to extend axons. In the developing spinal cord, newborn neurons extend axons towards their targets in response to cues from the surrounding tissues. Read more

Supervisors: Dr R Das, Dr S Herbert

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the role of spliceosome gene mutations in disease

The University of Manchester Faculty of Biology, Medicine and Health

The DNA of a cell is copied into a pre-messenger RNA (pre-mRNA) that the cell uses as a template for protein production. Some of the information contained in DNA is not required for making proteins, therefore, unwanted information must be removed before a protein is made. Read more

Supervisors: Prof R O'Keefe, Prof B Newman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Hungry tissues: Understanding how energy metabolism fuels morphogenesis

The University of Manchester Faculty of Biology, Medicine and Health

A vital aspect of multi-cellular life is morphogenesis, the process where the shape and size of an animal emerges from its constituent cells. Read more

Supervisors: Dr J.R.D Davis, Dr T Millard, Dr S Woolner, Prof E Amaya

Year round applications PhD Research Project Self-Funded PhD Students Only

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Characterisation of how pro-peptide regions of collagen control extracellular matrix homeostasis, in health and musculoskeletal diseases

The University of Manchester Faculty of Biology, Medicine and Health

Collagen-I (‘collagen’ from hereon) is the most abundant protein in the human body (circa 25% of total protein mass), providing structure to organs with very different functions (e.g. Read more

Supervisors: Dr JC Chang, Dr TZ Zacharchenko, Prof C Baldock

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 37 Cell Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Manchester

Cell Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Manchester

We have 37 Cell Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Manchester

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