University of Bradford Cell Biology PhD Research Projects PhD Projects, Programmes & Scholarships

We have 9 University of Bradford Cell Biology PhD Research Projects PhD Projects, Programmes & Scholarships

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Supervisors: Dr M Hussain, Dr C Willis, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Supervisors: Dr M Hussain, Dr M Katsikogianni, Dr N Javid

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of vitamin D3 in treating skin cancer and preventing drug resistance

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

During the last decade numerous studies have alluded to vitamin D. 3. playing a role in the prevention of cancer. Recent clinical trials looking at the potential role of vitamin D. Read more

Supervisors: Dr M Sutherland, Dr H Sheldrake, Dr S Kauser

Year round applications PhD Research Project Self-Funded PhD Students Only

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Polysialyltransferases as a target in metastatic cancer

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more

Supervisors: Prof R Falconer, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Supervisor: Dr H Sheldrake

Year round applications PhD Research Project Self-Funded PhD Students Only

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ERK5 MAPK signalling in Alzheimer’s disease

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available. Read more

Supervisors: Dr J Muller, Dr S Kantamneni

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

University of Bradford Faculty of Life Sciences

Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more

Supervisors: Prof K Pors, Dr V Vangala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Supervisors: Prof R Falconer, Prof P Loadman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Supervisors: Prof R Falconer, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 9 University of Bradford Cell Biology PhD Research Projects PhD Projects, Programmes & Scholarships

University of Bradford Cell Biology PhD Research Projects PhD Projects, Programmes & Scholarships

We have 9 University of Bradford Cell Biology PhD Research Projects PhD Projects, Programmes & Scholarships

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