University of Dundee Cell Biology PhD Projects, Programmes & Scholarships

We have 51 University of Dundee Cell Biology PhD Projects, Programmes & Scholarships

Investigating mechanisms of extra-cellular matrix remodelling and fibrosis in the gastrointestinal tract

Inflammatory bowel diseases, such as Crohn's disease, are increasing in prevalence globally. These are caused by chronic inflammation in the gut, there is no cure and medications are not effective for all. Read more

Supervisor: Dr M Mclean

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Mechanism, cellular consequences and pharmacological manipulation of Ras palmitoylation for the treatment of cancer

University of Dundee School of Medicine

In humans, the genes HRAS, NRAS and KRAS encode three closely related proteins frequently mutated in cancer promoting unregulated cell growth. Read more

Supervisors: Dr N Fraser, Dr G Masson

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Investigating how dormant senescent cells can drive drug-resistance following chemotherapy

University of Dundee School of Medicine

Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Using chemical-genetics to inhibit and characterise “undruggable” enzymes

University of Dundee School of Medicine

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Investigating Lysosomal Dysfunction in Ageing and Neurodegeneration

University of Dundee School of Medicine

Lysosomes are key cellular organelles that degrade and recycle macromolecules, act as signalling hubs and are implicated in many diseases including Parkinson’s disease (PD) and Alzheimer’s dementia (AD) where old age is a major risk factor. Read more

Supervisor: Dr E Sammler

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Characterisation of novel therapeutic approaches against invasive breast cancer

University of Dundee School of Medicine

Breast cancer is the most common cancer and the leading cause of death from cancer in women worldwide. Read more

Supervisor: Dr L de la Vega

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Investigating the role of RNA dependent DNA repair in childhood cancer

University of Dundee School of Medicine

Damage to our genetic material DNA is responsible for a wide range of human diseases including neurodegenerative diseases, haematological diseases, immune deficiencies, early ageing and cancers. Read more

Supervisor: Prof K Hiom

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

University of Dundee School of Medicine

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Supervisors: Dr L Kang, Dr C Murdoch

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Regulation and mechanics in polarity

University of Dundee School of Life Sciences

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

Supervisor: Dr D H Murray

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Is there a Role for Activated Akt in Palatogenesis?

University of Dundee Dental School

Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more

Supervisors: Dr S. J. Jones, Dr M Islam

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Development of micro-incubator OCT/ OCE bioreactor system to engineer a robust musculoskeletal tissue model

University of Dundee School of Science and Engineering

Achieving adequate musculoskeletal tissue healing is one of the most challenging factors in the repair of orthopaedic tissues. The problem of hard-to-soft tissue fixation is the major cause of failure of replacement grafts and leads to further musculoskeletal degeneration e.g. Read more

Supervisors: Dr J Vorstius, Dr C Li

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Interdisciplinary investigation of a large effect of sulfasalazine on HbA1c

University of Dundee School of Medicine

The anti-inflammatory drug sulfasalazine, which is used in rheumatoid arthritis and inflammatory bowel disease, was reported earlier to suppress HbA1c in a small cohort of patients [1]. Read more

Supervisors: Prof G Rena, Prof E Pearson

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Interdisciplinary investigation of the role of amino acids in immunometabolic responses to metformin in human cells

University of Dundee School of Medicine

There is overwhelming evidence that inflammation contributes to the development of cardiovascular disease (CVD) but counterbalancing this is evidence from meta-analysis of randomised control trials that many existing anti-inflammatory drugs, such as COX2 inhibitors and anti-TNF drugs, tend if anything to exacerbate risk of CVD. Read more

Supervisors: Prof G Rena, Prof C Lang

30 June 2024 PhD Research Project Self-Funded PhD Students Only

More Details

MSc by Research: Signaling pathways controlling epidermal development in cereals

University of Dundee School of Life Sciences

Plants living on land face brutal threats from pests, dehydration and temperature. To survive and thrive, land plants evolved a waxy ‘cuticle’ and distinctive epidermal cells such as gas pores and defensive barbs. Read more

Supervisor: Dr S McKim

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

We have 51 University of Dundee Cell Biology PhD Projects, Programmes & Scholarships

University of Dundee Cell Biology PhD Projects, Programmes & Scholarships

We have 51 University of Dundee Cell Biology PhD Projects, Programmes & Scholarships

University of Dundee

Select your nearest city

Do you want hassle-free information and advice?