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We have 11 Cell Biology (calcium) PhD Projects, Programmes & Scholarships

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Cell Biology (calcium) PhD Projects, Programmes & Scholarships

We have 11 Cell Biology (calcium) PhD Projects, Programmes & Scholarships

Alterations in reparative dentinogenesis with ageing, gender and genetic predisposition

Dental pulp exposure caused by tooth decay or injury can lead to life-threatening infections. Following injury, reparative dentinogenesis serves a vital purpose through the accelerated generation of tertiary dentine, comprising mineral and type I collagen. Read more

Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

PhD in stem cell modelling for neuropsychiatric disorders

This project provides a unique opportunity to explore the developmental origins of schizophrenia—a severe mental health disorder—using cutting-edge patient-derived stem cell models. Read more

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

SLS 3: Investigating the anti-inflammatory effects of artemisinin compounds on macrophages under systemic inflammatory conditions

Artemisinin compounds are safe and effective antimalarials. Recent evidence in our lab has shown these compounds also exert a potent anti-inflammatory effect by inhibiting neutrophil migration and the release of cytokines, chemokines and neutrophil extracellular traps. Read more

Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more
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