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We have 52 Cell Biology (interaction) PhD Projects, Programmes & Scholarships

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Cell Biology (interaction) PhD Projects, Programmes & Scholarships

We have 52 Cell Biology (interaction) PhD Projects, Programmes & Scholarships

In vitro modelling and investigation of skin ageing and the impact of negative stimuli

With an ageing population and the number of over 65s predicted to be 1 in 6 by 2050 there is a real need for targeted research to enhance the quality of life of this demographic. Read more

An Interdisciplinary Approach to Developing of Macrocyclic Inhibitors of the MAPK Pathway

Supervisory Team: Prof Ali Tavassoli . Project Description. We are seekign an outstanding chemistry student with an interest in chemical biology to work on a project to develop cyclic peptide inhibitors of a protein-protein interaction that is heavily implicated in the development and growth of tumours. . Read more

Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Obtaining an integrated understanding of oncogenic RAS signalling

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more

Exploring Uncharted Territories: Investigating the Impact of Follicular Fluid Extracellular Vesicles on Spermatozoa Function

The intricate dynamics underlying successful mammalian reproduction continue to captivate scientific inquiry. However, the mechanisms governing the interaction between spermatozoa and the female reproductive tract remain elusive. Read more

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