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We have 28 Cell Biology (synthesis) PhD Projects, Programmes & Scholarships

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Cell Biology (synthesis) PhD Projects, Programmes & Scholarships

We have 28 Cell Biology (synthesis) PhD Projects, Programmes & Scholarships

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Investigating monogenic disorders of the protein synthesis machinery

The University of Manchester Faculty of Biology, Medicine and Health
Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more
 Supervisors: Dr P Kasher, Dr S Banka, Prof G D Pavitt
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating Neuropeptide Signalling From Synthesis to Survival

University of Reading Department of Biomedical Sciences
Neuropeptides, comprising of short amino acid chains, are potent bioactive molecules with extensive neuromodulatory functions and are predominantly expressed within the central nervous system. Read more
 Supervisors: Dr A B Bicknell, Dr E Kevei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
 Supervisors: Prof R Falconer, Prof P Loadman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Fully Funded PhD Scholarship in Biomaterials Synthesis and Cartilage Tissue Engineering

University of Galway School of Medicine
Application(s) are invited from suitably qualified candidates for full-time funded PhD scholarship starting in September, 2024 affiliated to the School of Medicine at the University of Galway. Read more
 Supervisor: Dr T Mitra
 12 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the interaction of La related proteins with colliding ribosomes

The University of Manchester Faculty of Biology, Medicine and Health
Translation of mRNA into proteins is a critical cellular biological process for all life. This requires ribosomes to act with an array of translation factors to decode mRNA sequences. Read more
 Supervisors: Prof G D Pavitt, Dr A Roseman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Graphene oxide as growth factor carriers for meniscus tissue engineering

The University of Manchester Faculty of Biology, Medicine and Health
Damage to the meniscus of the knee leads to increased risk of osteoarthritis. Tissue engineering of a healthy meniscal fibrocartilage offers the opportunity to restore function. Read more
 Supervisors: Dr H Lu, Dr S Richardson, Prof P Xiao
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Elucidation of a new pathological mechanism for brittle bone disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
The incidence of the brittle bone disease osteogenesis imperfecta (OI) is estimated to be around 1 in 10,000 individuals. The phenotypic spectrum of OI ranges from mild to perinatal lethal and includes extra-skeletal connective tissue manifestations. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Engineering extracellular vesicles/exosomes for the treatment of ocular disease

Cardiff University Cardiff School of Optometry & Vision Sciences
Extracellular vesicles, also referred to as exosomes, are membrane‐bound particles containing huge numbers of proteins as well as genetic material in the form of RNA (mRNA and miRNA). Read more
 Supervisor: Dr B Mead
 5 August 2024  PhD Research Project  Self-Funded PhD Students Only
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Algal Bioplastics

University of Sheffield Department of Chemical & Biological Engineering
Single use plastic is a major environmental concern that is urgently in need of innovative solutions. Microalgae are photosynthetic organisms that can be employed to develop processes that are environmentally sustainable. Read more
 Supervisor: Dr S Vaidyanathan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Evaluating the impact of genotoxic aldehyde stress in premature ageing

University of Leicester Department of Chemistry
Aldehydes are highly reactive chemicals that are common pollutants and human metabolites. However, the vast majority of aldehydes’ biological functions are unknown. Read more
 Supervisors: Dr R Hopkinson, Dr K Tanaka
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders

University of Leeds Faculty of Biological Sciences
The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisor: Prof I Wood
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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‘Payload-Releasing Electrophiles’ – a new disease-selective delivery strategy for diagnostics and therapeutics

University of Leicester Department of Chemistry
Graduate Teaching Assistantship. This is a Graduate Training Assistantship (GTA), which means that you will be required to do some teaching, particularly lab demonstrating, as part of your training. Read more
 Supervisors: Dr R Hopkinson, Dr K Tanaka
 22 April 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Using laser-based microfabrication to develop the next generation of cellular analytics

University of Strathclyde Strathclyde Institute of Pharmacy & Biomedical Sciences
Background. The emerging microfabrication technology of ultrafast laser inscription [1] has opened the possibility of near arbitrary microfluidic device design. Read more
 Supervisors: Dr N Rattray, Prof G Burley
 30 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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