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We have 13 Cancer Biology (medicinal) PhD Projects, Programmes & Scholarships

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Cancer Biology (medicinal) PhD Projects, Programmes & Scholarships

We have 13 Cancer Biology (medicinal) PhD Projects, Programmes & Scholarships

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An Interdisciplinary Approach to Developing of Macrocyclic Inhibitors of the MAPK Pathway

University of Southampton Faculty of Engineering and Physical Sciences
Supervisory Team: Prof Ali Tavassoli . Project Description. We are seekign an outstanding chemistry student with an interest in chemical biology to work on a project to develop cyclic peptide inhibitors of a protein-protein interaction that is heavily implicated in the development and growth of tumours. . Read more
 Supervisor: Prof A Tavassoli
 31 August 2024  PhD Research Project  Competition Funded PhD Project (European/UK Students Only)
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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences
  Research Group: Medicines Development and Pharmaceutical Sciences
The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more
 Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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New Drugs for Brain Tumours: A Locoregional Implant Brain Tumours

University of Bradford Faculty of Life Sciences
  Research Group: Medicines Development and Pharmaceutical Sciences
Next-generation temozolomide derivatives for the treatment of high-grade glioma have been developed at the University of Bradford. Read more
 Supervisors: Dr R Wheelhouse, Prof A Paradkar, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Virology: Unique Antiviral Therapy targeting Zika and Related Viruses

University of Leeds Faculty of Medicine and Health
Zika Virus (ZIKV) has emerged as a new mosquito-borne threat to public health after the devastating South American outbreak. Read more
 Supervisors: Dr S Griffin, Dr A Kalli, Dr C McKimmie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology
What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more
 Supervisors: Dr JF Fox, Dr JH Hodgkinson
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more
 Supervisors: Dr J Muller, Prof R Falconer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Polysialyltransferases as a target in metastatic cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

University of Bradford Faculty of Life Sciences
Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more
 Supervisors: Prof K Pors, Dr V Vangala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
 Supervisors: Prof R Falconer, Prof P Loadman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Harnessing Breast Cancer Therapy: Innovative Formulation Strategies for Repurposing Medicines to Overcome Resistance

Kingston University Faculty of Health, Science, Social Care and Education
Background. Research in the Kadri group focuses on developing innovative chemical approaches for the discovery of novel therapeutics to address unmet global health needs. Read more
 Supervisor: Dr H Kadri
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mining the Hippo signalling pathway for novel anti-cancer therapeutics

Kingston University Faculty of Health, Science, Social Care and Education
Candidates are invited to join the Kadri Lab, where our research focuses on developing innovative chemical approaches for discovering novel therapeutics to address unmet global health needs. Read more
 Supervisor: Dr H Kadri
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding L1 ORF1p and Pin1 interaction to exploit it as a therapeutic strategy for liver cancer (ref: SF22/HLS/APP/SHUKLA)

Northumbria University Faculty of Health and Life Sciences
Primary liver cancer, predominantly hepatocellular carcinoma (HCC), is the 4th commonest cause of cancer death globally. Read more
 Supervisor: Dr R Shukla
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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