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We have 50 Cancer Biology (rna) PhD Projects, Programmes & Scholarships

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Cancer Biology (rna) PhD Projects, Programmes & Scholarships

We have 50 Cancer Biology (rna) PhD Projects, Programmes & Scholarships

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Defining the molecular mechanisms of leukaemia chemotherapies

The University of Manchester Faculty of Biology, Medicine and Health
Chemotherapies are usually the backbone of cancer treatment for either curative or palliative patient care. Multiple therapies can be used for the same disease, with the choice of drug dependent on parameters such as the patient’s age and fitness. Read more
 Supervisors: Dr JK Knight, Dr K Batta, Dr D Wiseman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular characterization of Sam68-driven cytoskeletal reorganization

University of Leicester Molecular and Cell Biology
The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more
 Supervisors: Dr C Dominguez, Prof A Fry
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy
Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more
 Supervisor: Dr G S Winkler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology
More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more
 Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Transcriptome homeostasis in cellular ageing and cancer

Queen Mary University of London Institute of Dentistry
Project Summary. We have previously established the oncogenic mechanisms of the transcription factor FOXM1 in perturbation of genome stability (1, 2), epigenome (3, 4) and adult progenitor epithelial stem cell proliferation (5). Read more
 Supervisor: Dr M T Teh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Next Generation Oligonucleotide Drugs for Gene Therapy

University of Portsmouth School of Pharmacy and Biomedical Sciences
Synthetic oligonucleotides are short strands of DNA that can be used to treat or manage a wide range of diseases, for example by silencing malfunctioning genes. Read more
 Supervisor: Dr D Rusling
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Prognostic Markers in Bladder Cancer

University of Worcester Research School
Bladder cancer is the ninth most common malignant disease in the world (Ferlay et al., 2015). Following removal of diseased tissue, cancer reoccurs in approximately 40% of patients and in 8% it metastasises into other tissues. Read more
 Supervisor: Dr A Cherry
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of extracellular vesicles in lung epithelial cell communication in health and disease

University of Salford School of Science, Engineering and Environment
There is an opportunity to apply for a widening participation scholarship (available to UK candidates or those eligible for UK fees) can be found here. Read more
 Supervisor: Dr P Miklavc
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cellular mechanisms of equal chromosome segregation and genome stability

University of Southampton School of Biological Sciences
The PhD project will investigate how chromosomes segregate equally in each cell division through epigenetic regulation of the centromere, and how cells respond in stress conditions to maintain genome instability. Read more
 Supervisor: Assoc Prof W.Y.K.Y. Yuen
 31 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Transcriptional kinases in cancer and developmental disorders

University of Leicester Molecular and Cell Biology
Cyclin-dependent kinases (CDKs) are protein kinases performing essential functions in regulation of cell cycle and transcription. Read more
 Supervisor: Dr MT Tellier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Ejecting infection: Understanding how epithelial tissues rid themselves of viral infections by apical extrusion

University of York York Biomedical Research Institute
Background. The epithelial tissues of our bodies use physical barriers and innate defences to fight viral infection. Read more
 Supervisor: Dr S Baker
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Short and long-distance communication in cancer: Feedback regulation of Ras signalling in tumourigenesis and cachexia

Cardiff University Cardiff School of Biosciences
Hamaratoglu Lab studies cell-cell signalling in development and tumourigenesis. We take advantage of outstanding genetic tools in Drosophila, and use larval imaginal discs as model epithelial organs. Read more
 Supervisors: Dr F Hamaratoglu, Dr C Hogan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health
The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more
 Supervisors: Dr G Mavria, Dr S Bell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Characterization of cyclin-dependent kinase 12 (CDK12) substrates and their roles in regulation of transcription and tumorigenesis

Masaryk University Faculty of Medicine
Doctoral study program. Life Sciences. Research area. RNA/nucleic acids research in health, cancer biology. Cdk12 is transcriptional cyclin-dependent kinase (Cdk) found mutated in various cancers. Read more
 Supervisor: Dr D Blažek
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

University of Portsmouth School of Pharmacy and Biomedical Sciences
Applications are invited for a self-funded, 3 year full-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. Read more
 Supervisors: Dr R Hadianamrei, Dr S Hafizi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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