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We have 24 Cancer Biology (structure) PhD Projects, Programmes & Scholarships

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Cancer Biology (structure) PhD Projects, Programmes & Scholarships

We have 24 Cancer Biology (structure) PhD Projects, Programmes & Scholarships

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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy
Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more
 Supervisor: Dr G S Winkler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self funded PhD in Biology: Structure and function of CIZ1

University of York Department of Biology
Lead supervisor: Prof Dawn Coverley. Co-supervisors: Prof Fred Antson. The student will be registered with the Department of Biology. Read more
 Supervisors: Prof D Coverley, Prof F Antson
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology
What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more
 Supervisors: Dr JF Fox, Dr JH Hodgkinson
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Obtaining insights into how a signalling hub protein Ras activates multiple effectors

University of Leicester Molecular and Cell Biology
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more
 Supervisors: Dr K Tanaka , Dr R Mahen
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Novel Molecules for Pancreatic Cancer Treatment

Loughborough University Department of Chemistry
At present there are no effective drugs for pancreatic cancer treatment. Several molecules have been shown to be a promising anti-austerity agents, able to suppress pancreatic cancer cell lines to tolerate conditions of nutrient deprivation. Read more
 Supervisor: Dr B Buckley
 1 July 2024  PhD Research Project  Self-Funded PhD Students Only
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Using supermarket loyalty cards data to study reproductive health

University of Bristol Bristol Medical School
Rationale. Shopping history records collected by supermarkets contain population level health information which could be missing from traditional health research data such as medical records. Read more
 Supervisors: Dr AS Skatova, Prof D Lawlor
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

University of Portsmouth School of Pharmacy and Biomedical Sciences
Applications are invited for a self-funded, 3 year full-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. Read more
 Supervisors: Dr R Hadianamrei, Dr S Hafizi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Engineering human tissue in vitro: development, characterisation, and application

Durham University Department of Biosciences
Tissues in the human body have a defined structure in that their growth and differentiation have developed in specific ways to create a cellular architecture… Read more
 Supervisor: Prof S Przyborski
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Revealing Reactivity in Cancer-Associated Heme Proteins: Novel Time-Resolved Structural Approaches

University of Leicester Molecular and Cell Biology
Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme involved in the degradation of tryptophan to kynurenine. Cancer cells upregulate IDO1 to escape normal immune responses and, in many cases, a high expression of IDO1 is connected to poor prognosis. Read more
 Supervisors: Dr HK Kwon, Dr P A Ash
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Molecular characterization of Sam68-driven cytoskeletal reorganization

University of Leicester Molecular and Cell Biology
The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more
 Supervisors: Dr C Dominguez, Prof A Fry
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Human Genetics, Genomics and Disease: Integrating fusion-proteins molecular signatures for advancing sarcoma diagnosis and therapy

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: MRC Human Genetics Unit
Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center, Berlin, Germany. Supervisors. Dr Nezha Benabdallah, Dr Daria Bunina. Read more
 Supervisor: Dr NB Benabdallah
 19 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Next Generation Oligonucleotide Drugs for Gene Therapy

University of Portsmouth School of Pharmacy and Biomedical Sciences
Synthetic oligonucleotides are short strands of DNA that can be used to treat or manage a wide range of diseases, for example by silencing malfunctioning genes. Read more
 Supervisor: Dr D Rusling
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer Epigenetics project

University of Otago Department of Pathology
Broad Project Summary: Cancer is a leading cause of morbidity and mortality worldwide. Epigenetic changes are now recognised as a hallmark feature of cancer, but our understanding of factors that are responsible for tumour spread still remains limited. Read more
 Supervisor: Assoc Prof A Chatterjee
 Year round applications  PhD Research Project  Awaiting Funding Decision/Possible External Funding
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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences
  Research Group: Medicines Development and Pharmaceutical Sciences
The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more
 Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of extracellular vesicles in lung epithelial cell communication in health and disease

University of Salford School of Science, Engineering and Environment
There is an opportunity to apply for a widening participation scholarship (available to UK candidates or those eligible for UK fees) can be found here. Read more
 Supervisor: Dr P Miklavc
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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