Biochemistry PhD Research Projects PhD Projects, Programmes & Scholarships in Dundee

We have 37 Biochemistry PhD Research Projects PhD Projects, Programmes & Scholarships in Dundee

Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Supervisors: Dr L Kang, Dr C Murdoch

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Targeting Ras palmitoylation for the treatment of cancer

University of Dundee School of Medicine

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Supervisor: Dr N Fraser

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Regulation and mechanics in polarity

University of Dundee School of Life Sciences

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

Supervisor: Dr D H Murray

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Is there a Role for Activated Akt in Palatogenesis?

University of Dundee Dental School

Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more

Supervisors: Dr S. J. Jones, Dr M Islam

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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MSc by Research: The Generation Gap – understanding tissue communication during grain development

University of Dundee School of Life Sciences

Cereal grain provides more calories than any other source to our diet, making grain production vital to food security. We study grain development in barley, a globally important cereal, and a powerful genetic model system. Read more

Supervisor: Dr S McKim

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Bacillus subtilis biofilm formation and environmental stress

University of Dundee School of Life Sciences

Bacillus subtilis is a Gram-positive, spore-forming bacterium that is widely used as a model organism to increase our understanding of biofilm formation. Read more

Supervisors: Prof N Stanley-Wall, Dr S Coulthurst

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: m6A modification of segmentation clock mRNAs and its role in somitogenesis

University of Dundee School of Life Sciences

During early embryogenesis, segments (somites) are formed during a process called somitogenesis. These somites will go on to form the bones and muscles of the skeleton. Read more

Supervisors: Prof J K Dale, Dr P Murray

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Degrade or die: Understanding proteasome regulation upon stress

University of Dundee School of Life Sciences

The Rousseau lab is interested in decoding how protein degradation by the proteasome is regulated in cells so that accumulation of unfolded, misfolded, or damaged proteins can be cleared before they become deleterious. Read more

Supervisor: Dr A Rousseau

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Molecular Analysis of Nuclear Bodies and RNP Trafficking Pathways in the Cell Nucleus

University of Dundee School of Life Sciences

Many important processes within mammalian cells are compartmentalised within specific subcellular structures. In the cell nucleus, Nuclear Bodies (NBs), such as nucleoli, provide specialised compartments that are not surrounded by membranes, but still concentrate specific proteins and RNAs. Read more

Supervisor: Prof A I Lamond

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Molecular characterisation of the factors driving lung fibrosis

University of Dundee School of Life Sciences

Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function. At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more

Supervisors: Prof S Arthur, Dr H McSorley

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Mapping the host response to fungal pathogens

University of Dundee School of Life Sciences

Fungal pathogens represent a significant clinical problem for which treatment options remain limited. Read more

Supervisor: Prof S Arthur

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells

University of Dundee School of Life Sciences

The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. Read more

Supervisor: Dr G Findlay

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: ADP-ribosylation in dementia and motor neuron disease

University of Dundee School of Life Sciences

ADP-ribosylation is a fundamental posttranslational modification where ADP-ribose is linked on to target proteins by ADP-ribose transferases and removed by the ADP-ribose hydrolases. Read more

Supervisor: Dr L McGurk

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

University of Dundee School of Life Sciences

T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more

Supervisor: Dr T Ly

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 37 Biochemistry PhD Research Projects PhD Projects, Programmes & Scholarships in Dundee

Biochemistry PhD Research Projects PhD Projects, Programmes & Scholarships in Dundee

We have 37 Biochemistry PhD Research Projects PhD Projects, Programmes & Scholarships in Dundee

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