Biochemistry PhD Projects, Programmes & Scholarships in Reading

We have 28 Biochemistry PhD Projects, Programmes & Scholarships in Reading

Understanding the cardiotoxic effects of anti-cancer therapies; a multidisciplinary approach

University of Reading Department of Biomedical Sciences

There are >18 million new cancer patients worldwide every year, of which >2 million are women with breast cancer. Read more

Supervisors: Prof P R Dash, Prof W Holderbaum, Prof S Nasuto, Prof N Derakhshan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Bowel cancer caused by bacteria

University of Reading Department of Biomedical Sciences

The gut microbiome has a profound effect on health and disease of humans and colorectal cancer (CRC) is one such disease influenced by microorganisms. Read more

Supervisors: Dr S R Clarke, Prof P R Dash

Year round applications PhD Research Project Self-Funded PhD Students Only

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Platelets in health, ageing and disease: new diagnostics and treatments

University of Reading Department of Biomedical Sciences

Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD), and also have roles in immunity, inflammation, cancer metastasis, Alzheimer's disease and a range of infections, such as dengue, HIV-1, malaria, and COVID-19. Read more

Supervisor: Dr CI Jones

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular Mechanisms of Receptor and Ion Channel Regulation in Pain and Inflammation

University of Reading School of Pharmacy

Are you ready to delve into the captivating world of molecular signaling and unravel the mysteries of the cardiovascular and nervous systems? We are thrilled to offer an exhilarating PhD opportunity at the forefront of scientific exploration. Read more

Supervisors: Dr G Cottrell, Prof D Widera, Dr S Amadesi

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the Therapeutic Potential of Cannabidiol (CBD) in Cardiac Fibrosis

University of Reading School of Pharmacy

Cardiac fibrosis is a condition that is characterized by the abnormal accumulation of fibrous tissue within the heart muscle and poses a significant threat to cardiovascular health. Read more

Supervisors: Dr G Cottrell, Prof D Widera

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigating Neuropeptide Signalling From Synthesis to Survival

University of Reading Department of Biomedical Sciences

Neuropeptides, comprising of short amino acid chains, are potent bioactive molecules with extensive neuromodulatory functions and are predominantly expressed within the central nervous system. Read more

Supervisors: Dr A B Bicknell, Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the mechanisms of antibacterial action of silver and copper ions and nanoparticles, and the emerging threat of metal-ion resistance

University of Reading Department of Biomedical Sciences

Project Overview. The emergence of bacterial strains with resistance to multiple classes of antibiotics has led to renewed interest in the antimicrobial properties of metals including silver. Read more

Supervisor: Dr G Mulley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating bacteria-bacteriophage diversity to develop phage libraries for treatment of bacterial infections

University of Reading Department of Biomedical Sciences

Project Overview. The World Health Organisation (WHO) predicts antimicrobial resistant (AMR) infections will be the leading cause of death globally by 2050. Read more

Supervisor: Dr G Mulley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Novel strategies for the diagnosis and treatment of snakebites

University of Reading School of Pharmacy

Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more

Supervisor: Prof SV Vaiyapuri

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular/inflammatory diseases

University of Reading School of Pharmacy

Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke. Read more

Supervisor: Prof SV Vaiyapuri

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the molecular mechanisms of thrombosis and haemostasis

University of Reading Department of Biomedical Sciences

Project Overview: . The risk of heart attack or stroke is elevated in obesity and in people with metabolic disorders such as diabetes. Read more

Supervisors: Dr C.E. Hughes, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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Bioinformatics studies of protein structures, functions and their interactions

University of Reading Department of Biomedical Sciences

The computational study of protein structures, functions and their interactions is fundamental to our understanding of disease. Read more

Supervisor: Prof L J McGuffin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Advancing Liquid Atmospheric Pressure (LAP) MALDI Mass Spectrometry

University of Reading School of Chemistry & Food

MALDI. mass spectrometry has been a cornerstone of modern biological mass. spectrometry, enabling the soft ionization, analysis and characterisation of. Read more

Supervisor: Prof R K Cramer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Pharmacological effects of cannabidiol (CBD) on mesenchymal stem cells in endometriosis

University of Reading School of Pharmacy

Endometriosis is a common long-term health condition that affects around 190 million women of reproductive age worldwide. It causes severe pain during periods, sex, going to the toilet, and sometimes just general pelvic discomfort, bloating, and tiredness. Read more

Supervisors: Prof D Widera, Dr G Cottrell

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Unravelling the Intricacies of Stress Hormone Regulation

University of Reading Department of Biomedical Sciences

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

Supervisor: Dr A B Bicknell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating lysosomal (dys)function in ageing and neurodegeneration

University of Reading Department of Biomedical Sciences

Project Overview. Ageing is associated with a decline in the functions of an organism (López-Otín, C. et al. Cell, 2023) and correlates with an increased risk of developing diseases in the later life (Niccoli, T. Read more

Supervisors: Dr S Cogo, Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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Protein engineering enzymes for Industry

University of Reading Department of Biomedical Sciences

Project Overview. We are interested in key features of the protein sequence - structure - function relationship, and how this information can be translated to health. Read more

Supervisor: Prof K A Watson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Toxic effects of breast cancer treatment on the heart: using artificial intelligence to predict the potential for heart failure

University of Reading Department of Biomedical Sciences

Project Overview. . Breast cancer is the most common cancer worldwide with ~15% of cases caused by a single gene, HER2. These women are treated with an antibody therapy (e.g. Read more

Supervisors: Prof A Clerk, Prof W Holderbaum, Prof S Nasuto

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using CRISPR in iPS cells to modify platelet function

University of Reading Department of Biomedical Sciences

Project Overview. Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus. Read more

Supervisor: Dr C.E. Hughes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Low density lipoprotein oxidation and atherosclerosis

University of Reading Department of Biomedical Sciences

Project overview. The research in Professor David Leake’s group is concerned with atherosclerosis, the underlying cause of coronary heart disease and thrombotic strokes. Read more

Supervisor: Prof D S Leake

Year round applications PhD Research Project Self-Funded PhD Students Only

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Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

University of Reading Department of Biomedical Sciences

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more

Supervisor: Dr S Boateng

Year round applications PhD Research Project Self-Funded PhD Students Only

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Multi-organ signalling and diseases. How maintaining skeletal muscle mass impacts the development of liver diseases

University of Reading Department of Biomedical Sciences

Skeletal muscle has a number of roles in the human body beyond locomotion. It has a vital role in controlling the metabolic activity the organism. Read more

Supervisor: Prof K Patel

Year round applications PhD Research Project Self-Funded PhD Students Only

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Systems level analysis of platelet signalling

University of Reading Department of Biomedical Sciences

We are interested in how intracellular signal transduction networks bring about complex biological behaviours in cells. We do this by combining computational biology with wet laboratory experimentation. Read more

Supervisors: Dr M J Fry, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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The regulation of platelet function - towards new strategies to prevent thrombosis

University of Reading Department of Biomedical Sciences

Project Overview. Platelets perform a pivotal role in the regulation of haemostasis, a physiological response to injury that prevents excessive bleeding. Read more

Supervisor: Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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Biological role of neuropeptides and their receptors

University of Reading School of Pharmacy

Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well. Read more

Supervisor: Dr L Lander

Year round applications PhD Research Project Self-Funded PhD Students Only

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Platelet-cell interactions: Platelets beyond thrombosis and haemostasis

University of Reading Department of Biomedical Sciences

Platelets play a key role in the prevention of bleeding following blood vessel damage. In addition to this important role, platelets also impact the… Read more

Supervisor: Dr A Pollitt

Year round applications PhD Research Project Self-Funded PhD Students Only

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Extracellular vesicles in health and disease

University of Reading Department of Food and Nutritional Sciences

Endothelial dysfunction (ED) is associated with classical and emerging risk factors of cardiovascular disease (CVD), correlates with disease progression and is an independent predictor of the risk of future cardiovascular events. Read more

Supervisors: Prof P Yaqoob, Dr D Tannetta

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes

University of Reading Department of Food and Nutritional Sciences

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more

Supervisors: Prof R A Frazier, Dr R Green

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 28 Biochemistry PhD Projects, Programmes & Scholarships in Reading

Biochemistry PhD Projects, Programmes & Scholarships in Reading

We have 28 Biochemistry PhD Projects, Programmes & Scholarships in Reading

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