University of Leeds Biochemistry PhD Projects, Programmes & Scholarships

We have 8 University of Leeds Biochemistry PhD Projects, Programmes & Scholarships

Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Supervisors: Dr G Mavria, Dr S Bell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Oncology: Evaluating Photodynamic Therapy in colorectal cancer using patient-derived organoids

University of Leeds Faculty of Medicine and Health

Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Surgery is first line treatment and often in adjunct with chemotherapy. Read more

Supervisors: Dr I Knot, Prof D Jayne

Year round applications PhD Research Project Self-Funded PhD Students Only

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Translational Medicine: Understanding the mechanism(s) of resistance to EPA to personalise therapy and improve outcome

University of Leeds Faculty of Medicine and Health

Advanced colorectal cancer (CRC) is the UK’s second most lethal cancer, with limited treatment options for unresectable metastatic tumours. Read more

Supervisors: Dr MA Volpato, Prof M Hull

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer Biology: The role of Wnt signaling in glioblastoma therapeutic resistance

University of Leeds Faculty of Medicine and Health

Glioblastoma is a deadly brain tumour treated with surgery, radiotherapy and chemotherapy with patient survival of 6-15 months. Read more

Supervisors: Dr G Mavria, Dr S Bell, Dr C Toomes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Supervisors: Dr F Errington-Mais, Dr V Jennings

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genetics: Unravelling the Norrin/beta-catenin signaling pathway and its role in retinal angiogenesis and blindness

University of Leeds Faculty of Medicine and Health

Our previous work on the genetic analysis of individuals with the inherited retinal disease Familial Exudative Vitreoretinopathy (FEVR), has helped identify a new angiogenesis pathway, the Norrin/beta-catenin pathway. Read more

Supervisors: Dr C Toomes, Dr J Bond, Dr S Bell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Complex 3D modelling of the tumour microenvironment for immunotherapy combination screening

University of Leeds Faculty of Medicine and Health

Cancer immunotherapy holds significant promise for the treatment of a range of cancers. Read more

Supervisors: Dr MA Volpato, Dr F Errington-Mais

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

University of Leeds Faculty of Medicine and Health

Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more

Supervisors: Prof L Houghton, Dr D Peckham

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 8 University of Leeds Biochemistry PhD Projects, Programmes & Scholarships

University of Leeds Biochemistry PhD Projects, Programmes & Scholarships

We have 8 University of Leeds Biochemistry PhD Projects, Programmes & Scholarships

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