Biochemistry (cardiac) PhD Projects, Programmes & Scholarships

We have 10 Biochemistry (cardiac) PhD Projects, Programmes & Scholarships

Investigating the Therapeutic Potential of Cannabidiol (CBD) in Cardiac Fibrosis

University of Reading School of Pharmacy

Cardiac fibrosis is a condition that is characterized by the abnormal accumulation of fibrous tissue within the heart muscle and poses a significant threat to cardiovascular health. Read more

Supervisors: Dr G Cottrell, Prof D Widera

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more

Supervisors: Dr M Hussain, Dr T Nasim, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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The effect of early-life stress on cardiac function in later life

University of Dundee School of Medicine

Stressful experiences in early childhood can increase the risk of cardiovascular disease (CVD) in later life. How early-life stress (ELS) influences susceptibility to CVD onset remains largely unknown. Read more

Supervisors: Dr N Fraser, Dr C Murdoch, Prof T Hales

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Beat-to-beat modulation of Calcium-induced Calcium release in cardiac muscle

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Contraction in the heart is well known to be dependent on a transient rise in intracellular calcium concentration. Read more

Supervisors: Dr M Hussain, Dr J Muller, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Toxic effects of breast cancer treatment on the heart: using artificial intelligence to predict the potential for heart failure

University of Reading Department of Biomedical Sciences

Project Overview. . Breast cancer is the most common cancer worldwide with ~15% of cases caused by a single gene, HER2. These women are treated with an antibody therapy (e.g. Read more

Supervisors: Prof A Clerk, Prof W Holderbaum, Prof S Nasuto

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

University of Dundee School of Medicine

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Supervisors: Dr L Kang, Dr C Murdoch

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Role of RyR2 posttranslational modification in arrhythmias

University of Otago Department of Physiology

Cardiac arrhythmias remain the leading cause of death in patients with heart disease. An important trigger for arrhythmias is the inappropriate opening of the cardiac ryanodine receptor (RyR2). Read more

Supervisor: Assoc Prof P Jones

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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The role of the extracellular matrix in cardiomyocyte developmental (SMITH_U24DTP1)

University of East Anglia Norwich Medical School

Primary Supervisor: Dr James Smith . Secondary Supervisor: Dr Iain Macaulay (EI) . Cardiomyocytes are the muscle cells of the heart, responsible for the production of contraction forces. Read more

Supervisor: Dr J Smith

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more

Supervisor: Dr EG Laird

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

University of Liverpool Institute of Life Course and Medical Sciences

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

Supervisor: Dr VPV Pekovic-Vaughan

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 10 Biochemistry (cardiac) PhD Projects, Programmes & Scholarships

Biochemistry (cardiac) PhD Projects, Programmes & Scholarships

We have 10 Biochemistry (cardiac) PhD Projects, Programmes & Scholarships

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