Biochemistry (design) PhD Projects, Programmes & Scholarships

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Supervisors: Prof R Falconer, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Bottom-Up Construction of a Synthetic Gap Junction

King’s College London School of Natural & Mathematical Sciences

Gap junctions play a crucial role in cellular communication, facilitating direct intercellular exchange of ions and small molecules. Read more

Supervisors: Prof M Wallace, Prof C Lorenz, Dr J Burrone

10 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Design and Folding of beta barrel membrane proteins

University of Leeds Faculty of Biological Sciences

The cell walls of Gram negative bacteria are packed with b-barrel outer membrane proteins (OMPs) whose function are essential for bacterial growth and virulence. Read more

Supervisors: Prof S E Radford, Prof D B Brockwell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting the mechanism of small GTPase splice variant RAC1B using ligand design

The University of Manchester Faculty of Biology, Medicine and Health

RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more

Supervisors: Dr RB Bryce, Dr S Butterworth, Dr T Jowitt, Dr A Ucar

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Supervisors: Prof R Falconer, Prof P Loadman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design and synthesis of next-generation antibody drug conjugates to target homologous recombination deficient cancers

University of Strathclyde Department of Pure and Applied Chemistry

Background. Antibody-drug conjugates (ADCs) offer a powerful strategy for the cell-selective delivery of therapeutics, while minimizing off-target interactions associated with the drug payload. Read more

Supervisors: Prof G Burley, Dr Z Rattray

3 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Sustainable Commodity Chemicals through Enzyme Engineering & Design (SuCCEED) - 4 posts available

The University of Manchester Department of Chemistry

SuCCEED is a BBSRC-funded Prosperity Partnership multi-million project between The University of Manchester and Shell. Commodity chemicals are produced on a global scale and normally derived from finite geological sources. Read more

Supervisors: Dr N Dixon, Dr J Esteban Serrano, Prof A Green, Prof D Leys, Dr V Spallina, Prof M Turner, Dr J Winterburn

30 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

University of Liverpool Institute of Life Course and Medical Sciences

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

Supervisor: Dr VPV Pekovic-Vaughan

Year round applications PhD Research Project Self-Funded PhD Students Only

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FAIROmics - PhD fellowship in plant-based food fermentation genomics.

INRAE Inrae - Paris-Saclay Food and Bioproduct Engineering Research Unit

About the Project. Plant-based dairy and meat alternatives have grown in popularity in recent years for various reasons, including sustainability and health benefits, as well as lifestyle trends and dietary restrictions. Read more

Supervisors: Dr MWB Wells-Bennik, Dr HB Bachmann, Dr EH Hester, Prof M Zwietering, Prof VV Valdramidis, Dr MD Dasenaki, Dr KA Karatzas

15 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Discovery and Development of Small Molecule Modulators of the Hippo Signalling Pathway for Enhanced Cancer Immunotherapy

Kingston University Faculty of Health, Science, Social Care and Education

Candidates are invited to join the Kadri Lab, where our research focuses on developing innovative chemical approaches for discovering novel therapeutics to address unmet global health needs. Read more

Supervisor: Dr H Kadri

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Better together: constructing tuneable fluorescent protein sensors for cellular imaging of protein-protein interactions

Cardiff University Cardiff School of Biosciences

Project Description. Protein-protein interactions (PPIs) commonly occur in biology with ~650,000 contributing to processes critical to human life. Read more

Supervisors: Prof D Jones, Dr PD Watson, Dr G Menzies, Dr R Clarkson

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 88 Biochemistry (design) PhD Projects, Programmes & Scholarships

Biochemistry (design) PhD Projects, Programmes & Scholarships

We have 88 Biochemistry (design) PhD Projects, Programmes & Scholarships

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