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We have 18 Biochemistry (immunohistochemistry) PhD Projects, Programmes & Scholarships

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Biochemistry (immunohistochemistry) PhD Projects, Programmes & Scholarships

We have 18 Biochemistry (immunohistochemistry) PhD Projects, Programmes & Scholarships

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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more
 Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Molecular Mechanisms of Receptor and Ion Channel Regulation in Pain and Inflammation

University of Reading School of Pharmacy
Are you ready to delve into the captivating world of molecular signaling and unravel the mysteries of the cardiovascular and nervous systems? We are thrilled to offer an exhilarating PhD opportunity at the forefront of scientific exploration. Read more
 Supervisors: Dr G Cottrell, Prof D Widera, Dr S Amadesi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Systemic infections accelerate tau spreading by promoting glial activation

University of Southampton School of Biological Sciences
Alzheimer’s disease (AD) is a neurodegenerative disease, with a complex biology. In this PhD project, we aim to explore the cellular and molecular mechanisms underlying tau pathology. Read more
 Supervisor: Prof J Teeling
 17 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Manganese is essential to human health and development. However, excess manganese is neurotoxic causing manganism, a neurodegenerative disorder characterised by dystonia-parkinsonism. Read more
 Supervisors: Dr K Tuschl, Dr P Mills, Dr WH Heywood
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more
 Supervisors: Dr M Hussain, Dr M Katsikogianni, Dr N Javid
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Polysialyltransferases as a target in metastatic cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the cellular functions of Trappc9 in brain development and microcephaly

University of Liverpool Institute of Systems, Molecular and Integrative Biology
This PhD project will investigate the cellular functions of the Trafficking protein particle complex subunit 9 (Trappc9) and its roles in brain development. Read more
 Supervisors: Dr A Plagge, Dr T Zech
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc By Research: Unravelling the mechanisms controlling anterior eye development

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Prof L Erskine, Prof N Vargesson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health
The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more
 Supervisors: Dr G Mavria, Dr S Bell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular mechanisms underlying the anti-atherogenic actions of natural products

Cardiff University Cardiff School of Biosciences
Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for most deaths in the western world with mortality increasing at a marked rate in developing. Read more
 Supervisors: Dr D Ramji, Dr T Hughes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of calcium signalling in regulating of tumour cell behaviour

University of Nottingham School of Life Sciences
Metastasis is the major cause of mortality in human cancers, yet we know relatively little of the fundamental biology that underlies the important transition to invasive malignancy. Read more
 Supervisors: Dr M Georgiou, Dr IM Maiellaro
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The use of Drosophila melanogaster to identify novel therapeutic agents for Alzheimer’s disease

University of Nottingham School of Life Sciences
Since 2003, our understanding of the causes of Alzheimer’s disease (AD) have improved considerably, however, in that time only one new drug treatment has been approved. Read more
 Supervisors: Dr M Georgiou, Dr Z Zhu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How to build and maintain a 3-dimensional polarised epithelial sheet

University of Nottingham School of Life Sciences
We are interested in how cells maintain normal cell shape within an epithelium. Correct epithelial cell shape is essential to maintain tissue integrity and when deregulated can cause diseases such as malignant cancers, diabetes, inflammation, and aging. Read more
 Supervisor: Dr M Georgiou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

University of Greenwich School of Pharmacy (Medway Campus)
The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more
 Supervisors: Dr F Papagiannouli, Dr G Lall
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

University of Kent Medway School of Pharmacy
The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more
 Supervisors: Dr F Papagiannouli, Dr G Lall
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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