Biochemistry (interaction) PhD Projects, Programmes & Scholarships

We have 42 Biochemistry (interaction) PhD Projects, Programmes & Scholarships

Natural products in bacterial physiology and chemical interaction

University of Leicester Department of Genetics and Genome Biology

Microbial natural products have diverse chemical structures and bioactivities, which range from cell-cell signalling, nutrient acquisition, antifungal and antibacterial activity to stress resistance (1). Read more

Supervisors: Dr C Jenul, Prof D Jones

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigating the impact of galectin-ligand interaction on cancer cell resistance to chemotherapeutic treatment

University of Liverpool Institute of Life Course and Medical Sciences

Galectins are multifunctional carbohydrate-binding proteins that are expressed by many types of human cells. Changes of galectin expression commonly occur in cancer (e.g. Read more

Supervisor: Prof LG Yu

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanisms and evolution of apicomplexan parasite/host interaction

University of Cambridge Department of Biochemistry

Apicomplexan parasites include disease agents responsible for malaria, toxoplasmosis, and other major diseases of humans and livestock. Read more

Supervisor: Dr Ross Waller

Year round applications PhD Research Project Awaiting Funding Decision/Possible External Funding

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Investigating the interaction of La related proteins with colliding ribosomes

The University of Manchester Faculty of Biology, Medicine and Health

Translation of mRNA into proteins is a critical cellular biological process for all life. This requires ribosomes to act with an array of translation factors to decode mRNA sequences. Read more

Supervisors: Prof G D Pavitt, Dr A Roseman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and functional investigation of the shared molecular mechanisms of host immunoregulation by the pathogens that cause malaria and sepsis.

University of York York Biomedical Research Institute

Infectious diseases cause enormous humanitarian and economic burdens worldwide. Designing interventions that prevent, cure, or control many infections is difficult because pathogens have evolved sophisticated ways of subverting host immunity. Read more

Supervisor: Prof GJ Wright

Year round applications PhD Research Project Self-Funded PhD Students Only

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Untangling the role of beta-1,3 glucan polymers in intercellular communication

University of Leeds Faculty of Biological Sciences

Apply to join the Benitez-Alfonso team in their quest to dissect the mechanisms underpinning the function of beta-1,3 glucan polymers in plant growth and development. . Read more

Supervisor: Dr Y Benitez-Alfonso

Year round applications PhD Research Project Self-Funded PhD Students Only

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Assessing the contribution of the human microbiome to paediatric cancer and predisposition and chromosomal instability syndromes

The University of Manchester Faculty of Biology, Medicine and Health

A self-funded PhD studentship is available in the laboratories of Andrew McBain, Stefan Meyer and Chris Knight. The project aims to study the microbiome in paediatric cancer predisposition and chromosomal instability syndromes (CIS). Read more

Supervisors: Prof A McBain, Dr S Meyer, Dr C Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

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Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Unravelling the mechanisms behind plant stress sensing

University of Oxford Department of Biology

Agricultural production and food security are severely threatened by the loss of arable land and climate change, with increasingly harsher droughts, floods, and heat waves reducing crop productivity by more than 50%. Read more

Supervisors: Dr J Bolla, Dr EBG Baena-Gonzalez

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Obtaining an integrated understanding of oncogenic RAS signalling

University of Leicester Molecular and Cell Biology

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more

Supervisor: Dr K Tanaka

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding and preventing the denaturation of proteins on surfaces in manufacture, storage and delivery of biotherapeutics

The University of Manchester Department of Materials

Protein and peptide therapeutics are pharmaceutical drug treatments derived from natural sources. They are applied to a range of diseases from diabetes to novel cancer therapies. Read more

Supervisors: Dr A Thomas, Prof A Saiani

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of microtubule regulators in the progression of cancer: investigating the link between BRCA2 and depolymerising kinesins.

University of Nottingham School of Life Sciences

The mitotic kinesin KIF2C/MCAK regulates microtubule length in the mitotic spindle and plays a role in preventing chromosome-microtubule attachment errors. Read more

Supervisors: Dr C Friel, Dr S Wheatley

Year round applications PhD Research Project Self-Funded PhD Students Only

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The Survivin Interactome in Health and Disease

University of Nottingham School of Life Sciences

Survivin is a small protein that is essential for life but that also contributes to disease, most notably cancer, in which its abnormal overexpression is linked to therapeutic resistance and metastasis. Read more

Supervisor: Dr S Wheatley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes

University of Reading Department of Food and Nutritional Sciences

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more

Supervisors: Prof R A Frazier, Dr R Green

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Supervisor: Prof T Gaunt

20 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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We have 42 Biochemistry (interaction) PhD Projects, Programmes & Scholarships

Biochemistry (interaction) PhD Projects, Programmes & Scholarships

We have 42 Biochemistry (interaction) PhD Projects, Programmes & Scholarships

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