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We have 34 Biochemistry (membrane) PhD Projects, Programmes & Scholarships

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Biochemistry (membrane) PhD Projects, Programmes & Scholarships

We have 34 Biochemistry (membrane) PhD Projects, Programmes & Scholarships

How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Membrane protein-metabolite interactions important in mitochondrial energy metabolism for burning fat as heat (CRICHTON_U24DTP)

Primary supervisor - Dr Paul Crichton . Secondary supervisor - Prof. Tom Clarke (UEA) . Mitochondria in our cells harness energy through the breakdown of nutrients to produce ATP through oxidative phosphorylation. Read more

Synthesis of Novel Organic Probes for the Study of Lipid-Lipid Interactions

Lipids are diverse and principal components of the cell and are involved in a vast array of processes ranging from their well-known structural importance in cell membranes, through to energy storage and participation in signalling pathways. Read more

Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more

Obtaining insights into how a signalling hub protein Ras activates multiple effectors

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more

Targeting Ras palmitoylation for the treatment of cancer

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more
Last chance to apply

Structural basis of two-component system signaling

Background: . As bacteria explore new habitats, go to war with competitors or collaborate against common enemies, they rely heavily on intra- and interspecies communication and precise molecular scouting of their environment. Read more

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