Biochemistry (peptide) PhD Projects, Programmes & Scholarships

We have 16 Biochemistry (peptide) PhD Projects, Programmes & Scholarships

Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

Queen’s University Belfast School of Pharmacy

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

Supervisor: Dr G Laverty

Year round applications PhD Research Project Self-Funded PhD Students Only

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New enzymatic routes for the synthesis of peptide therapeutics

The University of Manchester Department of Chemistry

Peptides are essential in life and are widely used as therapeutic agents, vaccines, biomaterials and in other important applications. Read more

Supervisor: Prof J Micklefield

19 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Supervisors: Prof R Falconer, Prof P Loadman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Fluorinated tools for chemical biology

University of Edinburgh School of Chemistry

A PhD studentship is available in the group of Dr Chris Coxon, School of Chemistry, University of Edinburgh, https://www.chem.ed.ac.uk/staff/academic-staff/dr-christopher-r-coxon. Read more

Supervisor: Dr C Coxon

31 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Unravelling the Intricacies of Stress Hormone Regulation

University of Reading Department of Biomedical Sciences

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

Supervisor: Dr A B Bicknell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more

Supervisors: Dr M Hussain, Dr T Nasim, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating Neuropeptide Signalling From Synthesis to Survival

University of Reading Department of Biomedical Sciences

Neuropeptides, comprising of short amino acid chains, are potent bioactive molecules with extensive neuromodulatory functions and are predominantly expressed within the central nervous system. Read more

Supervisors: Dr A B Bicknell, Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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ThAnoS: thiopeptide antibiotics biosynthesis (GHILAROV_J24DTP)

John Innes Centre Graduate Programme

Background. The acute problem of antimicrobial resistance incentivises us to develop innovative approaches to antibiotic discovery & production. Read more

Supervisor: Dr D Ghilarov

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Determine the efficacy of growth hormone receptor antagonism in hepatocellular carcinoma spheroid culture models

University of Auckland Liggins Institute

Hepatocellular carcinoma (HCC) is an aggressive and difficult to treat cancer with poor survival rates and limited systemic treatment options for advanced-stage disease. Read more

Supervisors: Dr Y Wang, Dr J Perry

28 February 2025 PhD Research Project Self-Funded PhD Students Only

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Use of a novel conjugation approach to generate a long-acting growth hormone receptor antagonist

University of Auckland Liggins Institute

Targeting the growth hormone (GH) signalling pathway could be an effective therapeutic approach for certain types of cancer. However, a lack of access to therapeutics that target GH or the GH receptor has hindered preclinical studies in this field. Read more

Supervisors: Dr Y Wang, Dr J Perry

30 August 2024 PhD Research Project Self-Funded PhD Students Only

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Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Chemical modification of proteins via metal-mediated processes

University of York York Biomedical Research Institute

Chemically modified proteins can be used to understand, treat, and diagnose disease. However, relatively few chemical reactions can be used to modify proteins, severely limiting the diversity and applications of new technologies. Read more

Supervisors: Dr C Spicer, Dr M Plevin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of a Long Acting Parathyroid Hormone Fusion for the Treatment of Hypoparathyroidism

University of Sheffield School of Medicine and Population Health

Background. Parathyroid hormone (PTH) is an 84 aa peptide produced by the parathyroid glands and is responsible for calcium homeostasis. Read more

Supervisors: Dr I Wilkinson, Prof J Newell-Price

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding and preventing the denaturation of proteins on surfaces in manufacture, storage and delivery of biotherapeutics

The University of Manchester Department of Materials

Protein and peptide therapeutics are pharmaceutical drug treatments derived from natural sources. They are applied to a range of diseases from diabetes to novel cancer therapies. Read more

Supervisors: Dr A Thomas, Prof A Saiani

Year round applications PhD Research Project Self-Funded PhD Students Only

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Taking Light Induced Electron Paramagnetic Resonance In Cell for Biological Structural Determination

The University of Manchester Department of Chemistry

Studying the structure of proteins and other biological systems is an important step in understanding their function. Most structural studies are conducted in environments that are far away from native conditions, such as those found inside a cell. Read more

Supervisors: Dr A Bowen, Dr J Rowbotham, Dr I Riddell, Dr D Heyes

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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We have 16 Biochemistry (peptide) PhD Projects, Programmes & Scholarships

Biochemistry (peptide) PhD Projects, Programmes & Scholarships

We have 16 Biochemistry (peptide) PhD Projects, Programmes & Scholarships

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