Biochemistry (protein crystallography) PhD Projects, Programmes & Scholarships

Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies

University of Leicester Molecular and Cell Biology

Whether a cell dies or not has profound consequences on health and disease. In healthy tissue, cells that acquire high levels of genetic damage are safely removed via a process of programmed cell death. Read more

Supervisor: Dr JF Fox

Year round applications PhD Research Project Self-Funded PhD Students Only

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The identification of allosteric inhibitors of high value therapeutic targets

University of Sheffield School of Biosciences

This study will develop a novel approach to identify allosteric inhibitor sites on a wide variety of high-value therapeutic targets, including protein kinases, protein phosphatases and small G-proteins. Read more

Supervisor: Prof J P Waltho

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and Development of Small Molecule Modulators of the Hippo Signalling Pathway for Enhanced Cancer Immunotherapy

Kingston University Faculty of Health, Science, Social Care and Education

Candidates are invited to join the Kadri Lab, where our research focuses on developing innovative chemical approaches for discovering novel therapeutics to address unmet global health needs. Read more

Supervisor: Dr H Kadri

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Mining the Hippo signalling pathway for novel anti-cancer therapeutics

Kingston University Faculty of Health, Science, Social Care and Education

Candidates are invited to join the Kadri Lab, where our research focuses on developing innovative chemical approaches for discovering novel therapeutics to address unmet global health needs. Read more

Supervisor: Dr H Kadri

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

University of Leicester Molecular and Cell Biology

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

Supervisor: Dr G Hall

Year round applications PhD Research Project Self-Funded PhD Students Only

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4-year PhD Studentship: Combatting bacterial zoonoses through multi-disciplinary studies of virulence factors

University of Bristol Bristol Veterinary School

Vector-borne diseases, including bacterial zoonoses, pose a significant threat to human and animal health and to livestock industries, particularly in low and middle-income countries. Read more

Supervisor: Dr T Cogan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

Supervisors: Dr H O'Hare, Dr N Garton

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Self funded PhD in Biology: Structure and function of CIZ1

University of York Department of Biology

Lead supervisor: Prof Dawn Coverley. Co-supervisors: Prof Fred Antson. The student will be registered with the Department of Biology. Read more

Supervisors: Prof D Coverley, Prof F Antson

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Structural Biology of Host-Parasite Interactions

Institute of Organic Chemistry and Biochemistry Prague Biochemistry and Molecular Biology

PhD Position in Structural Parasitology. A position for a talented and self-motivated PhD student is open in the structural biology group at IOCB Prague lead by Dr. Read more

Supervisor: Dr S Zoll

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology

More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more

Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Obtaining an integrated understanding of oncogenic RAS signalling

University of Leicester Molecular and Cell Biology

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more

Supervisor: Dr K Tanaka

Year round applications PhD Research Project Self-Funded PhD Students Only

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ThAnoS: thiopeptide antibiotics biosynthesis (GHILAROV_J24DTP)

John Innes Centre Graduate Programme

Background. The acute problem of antimicrobial resistance incentivises us to develop innovative approaches to antibiotic discovery & production. Read more

Supervisor: Dr D Ghilarov

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Structural basis of two-component system signaling

Max Planck Institute for Chemical Ecology International Max Planck Research School

Background: . As bacteria explore new habitats, go to war with competitors or collaborate against common enemies, they rely heavily on intra- and interspecies communication and precise molecular scouting of their environment. Read more

Supervisors: Prof UH Hellmich, Prof S.E.O. O'Connor

18 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Unravelling the mechanisms behind plant stress sensing

University of Oxford Department of Biology

Agricultural production and food security are severely threatened by the loss of arable land and climate change, with increasingly harsher droughts, floods, and heat waves reducing crop productivity by more than 50%. Read more

Supervisors: Dr J Bolla, Dr EBG Baena-Gonzalez

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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We have 16 Biochemistry (protein crystallography) PhD Projects, Programmes & Scholarships

Biochemistry (protein crystallography) PhD Projects, Programmes & Scholarships

We have 16 Biochemistry (protein crystallography) PhD Projects, Programmes & Scholarships

Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies

The identification of allosteric inhibitors of high value therapeutic targets

Discovery and Development of Small Molecule Modulators of the Hippo Signalling Pathway for Enhanced Cancer Immunotherapy

Mining the Hippo signalling pathway for novel anti-cancer therapeutics

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

4-year PhD Studentship: Combatting bacterial zoonoses through multi-disciplinary studies of virulence factors

Molecular level understanding of Mycobacterium tuberculosis

Self funded PhD in Biology: Structure and function of CIZ1

Structural Biology of Host-Parasite Interactions

Structural investigation of oncogenic splicing factors

Obtaining an integrated understanding of oncogenic RAS signalling

ThAnoS: thiopeptide antibiotics biosynthesis (GHILAROV_J24DTP)

Structural basis of two-component system signaling

Unravelling the mechanisms behind plant stress sensing

We have 16 Biochemistry (protein crystallography) PhD Projects, Programmes & Scholarships

Biochemistry (protein crystallography) PhD Projects, Programmes & Scholarships

We have 16 Biochemistry (protein crystallography) PhD Projects, Programmes & Scholarships

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