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We have 16 Biochemistry (risk analysis) PhD Projects, Programmes & Scholarships

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Biochemistry (risk analysis) PhD Projects, Programmes & Scholarships

We have 16 Biochemistry (risk analysis) PhD Projects, Programmes & Scholarships

Identifying causal pathways to disease using DNA methylation predicted blood traits.

Project Background. Blood cell types have been implicated in pathogenesis of chronic diseases. Genome wide association studies have identified thousands of variants associated with blood trait variation. Read more

Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks

The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children. Read more

Early Detection and Stratification of Dementia using Transformative Non-Invasive Holistic Optical Biomarker Technology in Biofluids

Supervisory Team: Professor Sumeet Mahajan, Professor Amrit Mudher, Professor Chris Kipps. Project description. Globally, there is a growing and a huge unmet need for tools and technologies that allow rapid, affordable and accurate dementia diagnosis. Read more

Investigating lysosomal (dys)function in ageing and neurodegeneration

Project Overview. Ageing is associated with a decline in the functions of an organism (López-Otín, C. et al. Cell, 2023) and correlates with an increased risk of developing diseases in the later life (Niccoli, T. Read more

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

Unravelling the role of genotoxic E. coli in colorectal cancer (SCHULLERS_U24BIGC)

Primary supervisor - Dr Stephanie Schüller. Secondary supervisor - Prof Nathalie Juge. Colorectal cancer (CRC) is the third most common and second most fatal cancer globally. Read more

Molecular mechanisms of the increase in maximal aerobic capacity (VO2max) with regular exercise

  Research Group: PENRG - Physiology Exercise and Nutrition Research Group
Performing regular exercise is crucial for good health and wellbeing, whereas failing to perform sufficient exercise increases the risk of diseases such as cardiovascular disease, type 2 diabetes, cancer, etc. Read more

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