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We have 17 Bioinformatics (evaluation) PhD Projects, Programmes & Scholarships

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Bioinformatics (evaluation) PhD Projects, Programmes & Scholarships

We have 17 Bioinformatics (evaluation) PhD Projects, Programmes & Scholarships

Exploration of deep learning based generative adversarial networks (GANs) to mitigate bias in the evaluation of medical images among diverse population and disease sub-groups

Medical image analysis using Deep Learning models involves training on progressively larger datasets. Homogeneity of data within the training set, particularly in its representation of diverse population sub-groups and various disease stages, substantially influences model effectiveness. Read more

NIHR Leeds BRC: Pre-clinical evaluation of novel regenerative medicine strategies for knee osteoarthritis

Historically, articular cartilage was considered incapable of spontaneous repair.  However, biomechanical correction in osteoarthritis (OA) using high tibial osteotomy or joint distraction demonstrated the remarkable joint to regeneration by “merely” correcting joint alignment. Read more

(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more

From bench to pre-clinical evaluation: a novel nucleic acid vaccine targeting tumour-associated antigens

Cancer and the long-term toxicities sustained from treatment remain a public health issue for adult and paediatric patients. The spread of tumour cells is believed to account for up to 90% of cancer-related morbidities. Read more

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
Last chance to apply

Computational simulation of nanomedicine for coronary microvascular disease

This is a four year collaborative studentship which requires the candidate to spend two full years based at Coventry University (UK) and two years based at A*STAR Research Institute (Singapore). Read more

An optimal framework for disease risk prediction and stratification for multi-ethnic populations (ref: SF22/HLS/APP/Chimusa)

The exceptional polygenicity of human traits makes unravelling mechanisms from disease risk prediction models daunting. The development of polygenic risk scores (PRS) methods, their evaluation and clinical utility have been explored almost in European ancestry Genome-Wide Association Studies (GWAS) data sets. Read more

Pulling the plug on antimicrobial resistance – novel antimicrobial compounds from The Roman Baths hot spring (Bath, UK)

Applications are invited for a three-year PhD studentship. The studentship will start on 1st October 2024. Project Description. Antimicrobial resistance (AMR) in bacterial, fungal and protozoan pathogens is a globally recognised threat to the treatment of infectious diseases. Read more

UCL SECReT: The International Training Centre for Security and Crime Research Degrees

UCL's Security Science Doctoral Research Training Centre (UCL SECReT) was founded in 2009 with support from the Engineering and Physical Sciences Research Council (ESRC) and an array of public and private sector organisations working in crime reduction security and law enforcement. Read more

Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Network-based predictive modelling of cardiovascular disease risk

The risk of cardiovascular disease (CVD) is orchestrated by multiple factors. QRISK models (currently QRISK3) have been used in the UK to estimate CVD risk within the next 10 years for individuals without CVD. Read more

17 Graduate Teaching Assistants (GTAs) in the Institute of Industry and Innovation

The Institute of Industry and Innovation (I2RI) at Sheffield Hallam University intends to appoint up to 17 GTAs on 3.5 year fixed-term, full-time studentships from October 2024, with annual stipend at the living wage foundation rate (currently £19,722 in the academic year 23/24). Read more

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