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We have 11 Bioinformatics (t cell) PhD Projects, Programmes & Scholarships

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Bioinformatics (t cell) PhD Projects, Programmes & Scholarships

We have 11 Bioinformatics (t cell) PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more

NIHR Leeds BRC: Pre-clinical evaluation of novel regenerative medicine strategies for knee osteoarthritis

Historically, articular cartilage was considered incapable of spontaneous repair.  However, biomechanical correction in osteoarthritis (OA) using high tibial osteotomy or joint distraction demonstrated the remarkable joint to regeneration by “merely” correcting joint alignment. Read more

Charting new neuronal survival pathways in Parkinson’s disease

The Neurodegenerative and Lysosomal Disease Laboratory is interested in uncovering the unknown molecular and cellular mechanisms of neurodegenerative diseases, particularly in the development of Parkinson’s disease and Batten disease. Read more

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Transcriptome biomarkers and mechanisms of chemoresistance

Project Summary. This project aims to identify biomarkers linked to the most potent multimodal anticancer therapy with the least toxicity to counteract hemoresistance in head and neck squamous cell carcinoma (HNSCC). Read more

Molecular mechanisms underlying the anti-atherogenic actions of natural products

Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for most deaths in the western world with mortality increasing at a marked rate in developing. Read more
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