Bioinformatics (dna) PhD Projects, Programmes & Scholarships

Transgenerational epigenetic consequences of pollution exposure.

University of Leicester Department of Genetics and Genome Biology

Project background. Environmental insults such as pollution can cause transgenerational negative health outcomes in both wild animal populations and humans. Read more

Supervisor: Dr H Marshall

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the genetic determinants of ultra-complex telomere fusion

Cardiff University Cardiff School of Medicine

We are seeking a motivated molecular biologist to study the mechanisms by which telomere dysfunction impacts cancer genomes. Read more

Supervisor: Prof D Baird

3 May 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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Nuclear and transcriptional dysregulations during cellular senescence

University of Leicester Molecular and Cell Biology

Cellular senescence, which is characterised by a proliferation arrest, is a driver of ageing (1). Several stresses can induce cellular senescence, including persistent DNA damage, telomere dysfunction, and oncogene activation. Read more

Supervisors: Dr MT Tellier, Dr Y Markaki

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Deconvoluting the spatial multi-omic landscape of high-grade glioma to target post-surgical residual disease

University of Sheffield School of Medicine and Population Health

Background. High-grade gliomas are the most common cancers arising within the brain and contribute to ~190,000 brain tumour related deaths/year globally. Read more

Supervisors: Dr S Collis, Dr O Rominiyi, Dr M Dunning

Year round applications PhD Research Project Self-Funded PhD Students Only

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A deep-learning approach to genomic regulation of tissue-specific alternative splicing

The University of Manchester Faculty of Biology, Medicine and Health

Each human gene is a blueprint for multiple distinct RNA transcripts that can be produced in differing quantities based on the localisation of the transcribing… Read more

Supervisors: Dr JE Eales, Prof T Papamarkou

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer Epigenetics project

University of Otago Department of Pathology

Broad Project Summary: Cancer is a leading cause of morbidity and mortality worldwide. Epigenetic changes are now recognised as a hallmark feature of cancer, but our understanding of factors that are responsible for tumour spread still remains limited. Read more

Supervisor: Assoc Prof A Chatterjee

Year round applications PhD Research Project Awaiting Funding Decision/Possible External Funding

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Fully funded PhD studentship in mechanisms of cancer heterogeneity and drug sensitivity

Ariel University Department of Molecular Biology

Treatment of cancer with drugs that cause DNA damage often leads to development of the drug tolerance. Recently, we uncovered a novel mechanism of such an adaptation that associates with active generation of hundreds of thousand mutations in chromosomes that prevent drug-triggered DNA damage. Read more

Supervisor: Prof M Sherman

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Using machine learning to predict cell-type specific effects of genetic variants which influence genome regulation

Imperial College London Department of Brain Sciences

UK Dementia Research Institute (UK DRI) Centre at Imperial. PhD Studentship in Machine Learning for Genomics. Imperial College London, White City Campus, London, UK. Read more

Supervisor: Dr N Skene

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Using machine learning to predict cell-type specific effects of genetic variants which influence genome regulation

Imperial College London Department of Brain Sciences

UK Dementia Research Institute (UK DRI) Centre at Imperial. PhD Studentship in Machine Learning for Genomics. Imperial College London, White City Campus, London, UK. Read more

Supervisor: Dr N Skene

Year round applications PhD Research Project Self-Funded PhD Students Only

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Characterization of cyclin-dependent kinase 12 (CDK12) substrates and their roles in regulation of transcription and tumorigenesis

Masaryk University Faculty of Medicine

Doctoral study program. Life Sciences. Research area. RNA/nucleic acids research in health, cancer biology. Cdk12 is transcriptional cyclin-dependent kinase (Cdk) found mutated in various cancers. Read more

Supervisor: Dr D Blažek

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Why do cancers cells re-express meiotic SYCP1 protein?

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The aim of meiosis is to generate gametes by recombining the chromosomes and reducing the genome from diploid to haploid. However, in mitosis haploid genome and recombination have catastrophic, oncogenic outcomes. Read more

Supervisor: Dr U McClurg

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded MSc R- The mechanisms driving heterogeneity and stemness during cellular transformation.

University of Bristol School of Cellular and Molecular Medicine

The mechanisms driving heterogeneity and stemness during cellular transformation. Read more

Supervisor: Dr A Essafi

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded PhD- The mechanisms driving heterogeneity and stemness during cellular transformation.

University of Bristol School of Cellular and Molecular Medicine

The mechanisms driving heterogeneity and stemness during cellular transformation. Read more

Supervisor: Dr A Essafi

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self funded MSc by research or PhD in Biology: Investigating chromosome segregation in thermophilic Archaea

University of York Department of Biology

Lead supervisor: Prof D Barilla. Co-Supervisor: Prof G Thomas. The student will be registered with the Department of Biology. Read more

Supervisor: Prof D Barilla

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Exploiting raptor genome sequences to combat wildlife crime

University of Leicester Department of Genetics and Genome Biology

Birds of prey have suffered persecution for centuries through trapping, shooting, poisoning and theft from the wild to meet the demand from egg collectors and falconers; they were also amongst the earliest beneficiaries of DNA testing in wildlife forensics. Read more

Supervisor: Dr C May

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 45 Bioinformatics (dna) PhD Projects, Programmes & Scholarships

Bioinformatics (dna) PhD Projects, Programmes & Scholarships

We have 45 Bioinformatics (dna) PhD Projects, Programmes & Scholarships

Transgenerational epigenetic consequences of pollution exposure.

Investigating the genetic determinants of ultra-complex telomere fusion

Nuclear and transcriptional dysregulations during cellular senescence

Deconvoluting the spatial multi-omic landscape of high-grade glioma to target post-surgical residual disease

A deep-learning approach to genomic regulation of tissue-specific alternative splicing

Cancer Epigenetics project

Fully funded PhD studentship in mechanisms of cancer heterogeneity and drug sensitivity

Using machine learning to predict cell-type specific effects of genetic variants which influence genome regulation

Using machine learning to predict cell-type specific effects of genetic variants which influence genome regulation

Characterization of cyclin-dependent kinase 12 (CDK12) substrates and their roles in regulation of transcription and tumorigenesis

Why do cancers cells re-express meiotic SYCP1 protein?

Self-funded MSc R- The mechanisms driving heterogeneity and stemness during cellular transformation.

Self-funded PhD- The mechanisms driving heterogeneity and stemness during cellular transformation.

Self funded MSc by research or PhD in Biology: Investigating chromosome segregation in thermophilic Archaea

Exploiting raptor genome sequences to combat wildlife crime

We have 45 Bioinformatics (dna) PhD Projects, Programmes & Scholarships

Bioinformatics (dna) PhD Projects, Programmes & Scholarships

We have 45 Bioinformatics (dna) PhD Projects, Programmes & Scholarships

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