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We have 61 Bioinformatics (treatment) PhD Projects, Programmes & Scholarships

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Bioinformatics (treatment) PhD Projects, Programmes & Scholarships

We have 61 Bioinformatics (treatment) PhD Projects, Programmes & Scholarships

NIHR Leeds BRC: Multimodal predictive modelling of outcome in patients with gastrointestinal cancer

Worldwide, cancer of the upper (oesophagus, stomach) and lower gastrointestinal (colon and rectum) tract is newly diagnosed in 3.6 million patients every year and 2.2 million patients die from this disease every year. Read more

Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Novel strategies for the diagnosis and treatment of snakebites

Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more

Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more
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Computational simulation of nanomedicine for coronary microvascular disease

This is a four year collaborative studentship which requires the candidate to spend two full years based at Coventry University (UK) and two years based at A*STAR Research Institute (Singapore). Read more

From bench to pre-clinical evaluation: a novel nucleic acid vaccine targeting tumour-associated antigens

Cancer and the long-term toxicities sustained from treatment remain a public health issue for adult and paediatric patients. The spread of tumour cells is believed to account for up to 90% of cancer-related morbidities. Read more

Engineering AI and deep learning approaches for digital pathology and bioimaging

An exciting opportunity to join a dynamic and multidisciplinary group at the School of Cancer and Pharmaceutical Sciences. You will develop new computational pathology approaches to improve cancer patient treatment and diagnosis. Read more

Integrated omics approach to psychiatric disorders

  Research Group: Chemistry and Biosciences
In psychiatry, the selection of antipsychotics and antidepressants is led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). Read more

Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

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