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We have 25 Neuroscience (blood) PhD Projects, Programmes & Scholarships

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Neuroscience (blood) PhD Projects, Programmes & Scholarships

We have 25 Neuroscience (blood) PhD Projects, Programmes & Scholarships

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When do astrocytes contribute to the control of brain blood flow?

University of Sheffield Department of Psychology
In order that the brain can function normally, it is essential that blood flow within the brain is well matched to neuronal metabolic demand. Read more
 Supervisor: Dr C Howarth
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Neurovascular coupling in cerebral hypoperfusion

The University of Manchester Faculty of Biology, Medicine and Health
There are almost a million people living with dementia in the UK. Most of these cases comprise Alzheimer’s Disease (AD), vascular dementia (VaD) or, as is increasingly recognised, a mixed picture phenotype with evidence of the two conditions co-existent in the same patient. Read more
 Supervisors: Dr H Pritchard, Dr A Greenstein, Dr I Schiessl, Prof S Allan
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Simultaneous measures of brain and blood oxygenation: Revealing the function behind ‘functional’ brain mapping signals

University of Sheffield Department of Psychology
A technique called blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) can determine levels of different activity in parts of the living human brain and how malfunctions can occur in disease. Read more
 Supervisors: Dr M Jones, Dr J Berwick
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Feeding microbes to protect the brain: does the gut microbiota mediate the risk-reducing effects of a healthy diet on Alzheimer’s disease?

Queen Mary University of London Institute of Dentistry
Background. Ways of reducing the risk of developing Alzheimer’s disease (AD) and other dementias are critically needed, given the almost total lack of truly effective therapeutic options, even despite newer anti-amyloid drugs1. Read more
 Supervisors: Dr S McArthur, Dr E Hagi-Pavli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Computational modelling of the human blood-brain barrier to tackle multidrug resistance and neurodegenerative disorders (molecular dynamics/deep generative learning/AI)

University of Portsmouth School of Pharmacy and Biomedical Sciences
By 2050 the number of people living with neurodegenerative disorders are set to double. Alzheimer’s disease in particular is set to become a public health emergency. Read more
 Supervisor: Prof C Jorgensen
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Neurotransmitters, brain blood flow and functional brain imaging signals.r

University of Sheffield Department of Psychology
The function of modulatory neurotransmitter systems such as serotonin, dopamine or acetylcholine are implicated in a wide range of brain diseases and are targeted by a wide range of therapeutic drugs. Read more
 Supervisor: Dr C Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A 3D-Printed Blood-Brain-Barrier-on-a-Chip for Agrochemical Permeability Studies – CASE Studentship

University of Liverpool Department of Physics
The blood-brain barrier (BBB) tightly regulates the flow of material between the bloodstream and the brain. One of the big problems faced by a range of sectors, from pharmaceuticals to agrochemicals, is understanding how compounds interact with and cross this barrier. Read more
 Supervisors: Dr J Forth, Dr D Dickens
 1 June 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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The neurophysiological basis of spontaneous fluctuations in neuroimaging signals

University of Sheffield Department of Psychology
A technique called blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) can determine levels of different activity in parts of the living human brain and how malfunctions can occur in disease. Read more
 Supervisors: Dr M Jones, Dr J Berwick
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Prenatal and pre-conception effects on neurodevelopmental disorders.

University of Bristol Bristol Medical School
Rationale. There is growing concern that paternal exposures before conception have been greatly neglected. Studying how these impact on future generations’ health could open new avenues for prevention-prospective fathers are not generally advised to change their behaviour. Read more
 Supervisors: Dr L Zuccolo, Dr G Sharp, Dr D Caramaschi, Prof A Thapar
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Cancer Biology: The role of Wnt signaling in glioblastoma therapeutic resistance

University of Leeds Faculty of Medicine and Health
Glioblastoma is a deadly brain tumour treated with surgery, radiotherapy and chemotherapy with patient survival of 6-15 months. Read more
 Supervisors: Dr G Mavria, Dr S Bell, Dr C Toomes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using pharmacological agents to investigate the mechanisms of the neuronal vascular coupling

University of Sheffield Department of Psychology
The changes in cerebral blood flow, volume and oxygenation that accompany increases in neural activity form the basis of non-invasive neuroimaging techniques such as blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) which allow human brain mapping. Read more
 Supervisor: Dr J Berwick
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding neurovascular coupling and its importance in the interpretation of modern neuroimaging techniques

University of Sheffield Department of Psychology
During the past two decades, blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) has become the scientific technique of choice for investigating human brain function in the field of cognitive neuroscience. Read more
 Supervisor: Dr J Berwick
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Function Brain imaging in disease: what are the activation maps really telling us?

University of Sheffield Department of Psychology
Functional brain imaging methods such as functional magnetic resonance imaging (fMRI) have already revolutionized how we can study the processes and functioning of the healthy human brain and are making an increasing impact on our understanding on what goes wrong in disease of the brain. Read more
 Supervisor: Dr C Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How GABA neurones in the DVC control glucose metabolism

University of Leeds Faculty of Biological Sciences
The Dorsal Vagal Complex (DVC) of the brain is an important regulator of glucose metabolism and food intake. The Nucleus of the Solitary Tract (NTS) in the DVC senses insulin and triggers a neuronal relay to decrease hepatic glucose production (HPG) in rodents. Read more
 Supervisors: Dr B.M. Filippi, Dr J. Johnston
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MScR: Involvement of astrocytes in neurological manifestations of Long COVID syndrome

University of Bristol School of Physiology, Pharmacology & Neuroscience
A significant fraction of patients affected by Long COVID, long-term consequences following acute SARS-CoV-2 infection, suffer from mental fatigue and cognitive deficits (1-3). Read more
 Supervisor: Prof A Teschemacher
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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