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We have 21 Neuroscience (mass) PhD Projects, Programmes & Scholarships

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Neuroscience (mass) PhD Projects, Programmes & Scholarships

We have 21 Neuroscience (mass) PhD Projects, Programmes & Scholarships

Investigating the links between β-amyloid, osteoporosis and frailty in Alzheimer’s disease

Background. Individuals with Alzheimer’s disease are more likely to suffer from osteoporosis (the loss of bone mass and strength) than age-matched individuals1, significantly contributing to the frailty associated with dementia. Read more

The effect of low protein diet on the development of the neuromuscular system

Age-related sarcopenia is characterised by reduction in the number of myofibres and motor neurons and an additional weakening of the remaining fibres, causing reduction in muscle mass and function. Read more

How does SUMOylation regulate cell survival and death in Heat Shock Response?

Heat shock response (HSR) is a universally existing essential phenomenon for all living organisms to survive sudden increases in environmental temperature that have pronounced damaging effects on important cellular structures and functions (1). Read more

Fully Funded PhD Program Opportunity

The Okinawa Institute of Science and Technology Graduate University (OIST), accredited in 2011 as a graduate university, is located in the beautiful subtropical island of Okinawa, Japan. Read more

Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation

This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more

Investigating the role of Aquaporins in age related diseases

Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more

Epilepsy and the ageing brain

Our ability to remember ‘where I put my car keys today’ instead of ‘where I put them yesterday’ depends on a computational process called pattern separation. Read more

Pain increases disability; disability increases pain: Understanding the vicious cycle.

Arthritis affects 10 million people in the UK, and is on the rise. Many do not respond adequately to treatment. Pain is the main symptom, a leading cause of disability and worsens the risk of developing other health issues. Read more

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

  Research Group: Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

MSc by Research: Nutrient-dependent regulation of microglia function and immune responses

Microglia are constantly sensing the brain environment for metabolic changes, damage and pathogenic invasion. Microglia are highly metabolically active, with activation in response to inflammatory stimulation increasing glycolytic demand. Read more

MSc by Research: Understanding the functions of ERphagy via its targeted cargos

The selective degradation of the endoplasmic reticulum via autophagy, also known as ERphagy, is a fundamental cellular process that has been observed under different stresses and stimuli. Read more

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