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We have 18 Neuroscience (metabolism) PhD Projects, Programmes & Scholarships

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Neuroscience (metabolism) PhD Projects, Programmes & Scholarships

We have 18 Neuroscience (metabolism) PhD Projects, Programmes & Scholarships

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How GABA neurones in the DVC control glucose metabolism

University of Leeds Faculty of Biological Sciences
The Dorsal Vagal Complex (DVC) of the brain is an important regulator of glucose metabolism and food intake. The Nucleus of the Solitary Tract (NTS) in the DVC senses insulin and triggers a neuronal relay to decrease hepatic glucose production (HPG) in rodents. Read more
 Supervisors: Dr B.M. Filippi, Dr J. Johnston
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Dissecting the interplay of extracellular vesicle signalling and tryptophan metabolism in schizophrenia pathogenesis

University of Leicester Department of Genetics and Genome Biology
L-kynurenine (KYN) and kynurenic acid (KYNA) are metabolites of the kynurenine pathway (KP) of tryptophan degradation and have been found to be increased in the brains of patients with schizophrenia. Read more
 Supervisor: Prof F Giorgini
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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An assessment of the effects of healthy ageing and transcranial Direct Current Stimulation (tDCS) on human foraging cognition

University of Leicester School of Psychology and Vision Sciences
Identifying cognitive markers of human heathy ageing is of extreme importance considering that global population over age 65 is expected to increase by 120% by 2050. Read more
 Supervisors: Dr C De Lillo, Prof E B. Mukaetova-Ladinska
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Self funded MSc by Research or PhD in Biology: Ion channel signalling in cancer cells

University of York Department of Biology
Lead supervisor: Dr W Brackenbury. The student will be registered with the Department of Biology. Our cells constantly sense and transport ions present in their environment. Read more
 Supervisor: Dr W Brackenbury
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Exploring the interplay between ageing, gut microbiome, and neurodegenerative diseases

University of Reading Department of Biomedical Sciences
Project Overview. Neurodegenerative disorders such as Parkinson’s and Alzheimer’s disease represent major health risks in ageing societies. Read more
 Supervisor: Dr E Kevei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Ion channel signalling in cancer cells

University of York York Biomedical Research Institute
Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing. Read more
 Supervisor: Dr W Brackenbury
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MScR: Involvement of astrocytes in neurological manifestations of Long COVID syndrome

University of Bristol School of Physiology, Pharmacology & Neuroscience
A significant fraction of patients affected by Long COVID, long-term consequences following acute SARS-CoV-2 infection, suffer from mental fatigue and cognitive deficits (1-3). Read more
 Supervisor: Prof A Teschemacher
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Precision Therapy for NBAS-related disorder

University of Sheffield School of Medicine and Population Health
It is very well recognised that rare diseases offer the potential to uncover new information about mechanisms underlying a range of phenotypes. Read more
 Supervisor: Dr M Balasubramanian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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In silico modelling of endocannabinoid evolution

University of Worcester Research School
In the brain, the endocannabinoid (eCB) system maintains adequate neurotransmission (Lu and Mackie 2016). Indeed, the eCB system provides a negative feedback mechanism, preventing over-activation of synaptic transmission. Read more
 Supervisor: Dr M Di Micelli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Measuring the brain's energy dynamics to establish crucial biomarkers for mood disorders

Brighton & Sussex Medical School Post-graduate Research
The brain is one of the most metabolically active organs in the body, consuming a disproportionately large amount of energy compared to its size. Read more
 Supervisors: Dr I Asllani, Dr A Colasanti
 30 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Development of LA1011 for high affinity binding to Hsp90 for use towards healthy ageing in patients showing Alzheimer’s symptoms

University of Sussex School of Life Sciences
  Research Group: Biochemistry
With 50 million global cases of Alzheimer’s disease (AD) and care costs of 1 trillion UK pounds (expected to triple by 2050), there is a pressing need to slow disease progression, sustain productive lives and reduce costs. Read more
 Supervisor: Dr C Prodromou
 5 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Immune and metabolomic profile of Copy Number Variation associated with high risk of psychiatric and cardiometabolic conditions

Cardiff University Cardiff School of Medicine
Hodge Centre for Translational Neuroscience. “Towards innovative treatments for mental illness”. Cardiff University Neuroscience and Mental Health Innovation Institute. Read more
 Supervisor: Dr M van den Bree
 7 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Pain increases disability; disability increases pain: Understanding the vicious cycle.

University of Nottingham School of Medicine
Arthritis affects 10 million people in the UK, and is on the rise. Many do not respond adequately to treatment. Pain is the main symptom, a leading cause of disability and worsens the risk of developing other health issues. Read more
 Supervisors: Dr SS Smith, Dr M Piasecki, Assoc Prof FM Moffatt
 30 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Investigating the cellular functions of Trappc9 in brain development and microcephaly

University of Liverpool Institute of Systems, Molecular and Integrative Biology
This PhD project will investigate the cellular functions of the Trafficking protein particle complex subunit 9 (Trappc9) and its roles in brain development. Read more
 Supervisors: Dr A Plagge, Dr T Zech
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Metabolic modulation of microglial homeostasis and immune response

Kingston University Faculty of Health, Science, Social Care and Education
Microglia are a specialised immune cell found in the central nervous system. They are responsible for maintaining brain homeostasis and play an important role in the early onset and development of neuroinflammatory disorders such as Alzheimer’s disease. Read more
 Supervisor: Dr M Stolinski
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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