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We have 10 Neuroscience (spectrometry) PhD Projects, Programmes & Scholarships

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Neuroscience (spectrometry) PhD Projects, Programmes & Scholarships

We have 10 Neuroscience (spectrometry) PhD Projects, Programmes & Scholarships

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

  Research Group: Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

MSc by Research: Nutrient-dependent regulation of microglia function and immune responses

Microglia are constantly sensing the brain environment for metabolic changes, damage and pathogenic invasion. Microglia are highly metabolically active, with activation in response to inflammatory stimulation increasing glycolytic demand. Read more

MSc by Research: Understanding the functions of ERphagy via its targeted cargos

The selective degradation of the endoplasmic reticulum via autophagy, also known as ERphagy, is a fundamental cellular process that has been observed under different stresses and stimuli. Read more

Chromatin remodelling complexes in human brain development

Chromatin regulators are a group of proteins that control the way the rest of the genome is opened up and “read” by the cellular machinery, with fundamental roles in development and disease. Read more

Exosome biogenesis and organelle trafficking in neurodegeneration.

Scientific summary. Intracellular transport pathways are fundamental for cell structure and function. Due to their longevity, complex morphology (long axonal and dendritic extensions) and requirement to maintain synaptic transmission, neurons are heavily dependent upon intracellular transport. Read more

Investigating monogenic disorders of the protein synthesis machinery

Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more
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