Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

We have 30 Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

Urokinase-plasminogen activator as a target to block osteoarthritic cartilage destruction

University of Liverpool Institute of Life Course and Medical Sciences

Osteoarthritis (OA) is one of the major causes of disability globally, which is particularly significant in an ageing population. Read more

Supervisor: Dr D Wilkinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Engineering polysaccharide sulfotransferases

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The ENZACT Prosperity Partnership is led by UCL and brings together five Universities and two major MNCs. The Liverpool component of ENZACT is focussed on enzymatic sulfation. Read more

Supervisors: Prof D G Fernig, Dr E A Yates, Dr IB Barsukov

14 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics

Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more

Supervisor: Dr RB Burton

1 July 2024 PhD Research Project Self-Funded PhD Students Only

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Study of early pathological changes in calcified cartilage in osteoarthritis and alkaptonuria

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

We are seeking a motivated individual to work on this exciting project investigating the role that the calcified cartilage has in rare and common joint osteoarthritis, using novel approaches such as gene silencing and establishment of a 3D chondrocyte cell culture model. Read more

Supervisor: Dr JH Hughes

10 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Development of novel therapies for Hirschsprung’s Disease

University of Liverpool Faculty of Health and Life Science

As a PhD student, you'll be part of a groundbreaking project aiming to revolutionise the treatment landscape for Hirschsprung's Disease (HSCR). Read more

Supervisors: Miss RH Harwood, Dr B Wilm, Miss SA Almond

26 April 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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Translating protection of cell-surface receptor LRP1 into potential disease-modifying therapies for osteoarthritis.

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Osteoarthritis (OA) causes pain and disability and is the most prevalent age-related joint disorder worldwide but there are no disease-modifying drugs available. Read more

Supervisors: Dr K Yamamoto, Prof G Bou-Gharios

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

University of Liverpool Institute of Life Course and Medical Sciences

Immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) affect millions of people worldwide and cause debilitating and disabling musculoskeletal disease. Read more

Supervisors: Dr HL Wright, Prof MJ Peffers

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of neutrophil-mediated tissue damage in a model of lupus nephritis

University of Liverpool Institute of Life Course and Medical Sciences

Systemic lupus erythematosus (SLE) is a rare autoimmune disease that affects around 5 million people worldwide. It disproportionately affects women and is incurable. Read more

Supervisors: Dr HL Wright, Dr D Wilkinson, Dr D Turner

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using pre-clinical models of disease to define new targets to slow joint degeneration in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences

The main overall aim of this project is to understand mechanisms of joint degeneration during osteoarthritis progression in order to define new targets for therapy. Read more

Supervisor: Dr B Poulet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of Aquaporins in age related diseases

University of Liverpool Institute of Life Course and Medical Sciences

Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more

Supervisor: Dr C Staunton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Control of bone shape and function by the extracellular matrix Fibrillin-1

University of Liverpool Institute of Life Course and Medical Sciences

Bones are tightly regulated structures that remodel their structure to adapt to changes in their mechanical environment. With ageing, this mechanical response is often dampened, leading to bone loss and weakness. Read more

Supervisor: Dr B Poulet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Uncovering the mechanochemical signalling inputs that drive gastruloid axial patterning

University of Liverpool Institute of Life Course and Medical Sciences

How the early mammalian embryo converts a mass of identical cells in an organism with multiple axes of symmetry (anteroposterior, dorsoventral, mediolateral) is a critical question in developmental biology. Read more

Supervisor: Dr D Turner

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of oxidative metabolites in joint destruction in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences

We are seeking a motivated researcher to work on a pioneering project investigating the role of oxidative stress in alkaptonuria (AKU) and associated conditions. Read more

Supervisors: Dr BN Norman, Dr JH Hughes, Prof G Bou-Gharios

Year round applications PhD Research Project Self-Funded PhD Students Only

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Exploring tyrosine metabolism as a source of oxidative stress

University of Liverpool Institute of Life Course and Medical Sciences

We are seeking a motivated researcher to work on a pioneering project investigating the role of oxidative stress associated with tyrosine metabolism. Read more

Supervisors: Dr BN Norman, Dr JH Hughes, Prof L Ranganath

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Determination of the non-coding RNAs in the knee joint tissues of dogs at differing risk to cranial cruciate ligament rupture.

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Background. The cranial cruciate ligment (CCL) is the most frequently damaged ligament of the canine knee joint following injuries and age-related ligament breakdown, leading to the development of osteoarthritis (OA). Read more

Supervisors: Prof E Comerford, Prof M Peffers

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 30 Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

We have 30 Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

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