We have 29 Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in London

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Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in London

We have 29 Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in London

Last chance to apply

Investigation of novel glycoconjugate vaccines to produce mucosal and systemic immunity against Group A Streptococcus.

Medicines and Healthcare Products Regulatory Agency Vaccines team

Glycoconjugate vaccines have shown to be effective for several mucosal pathogens such as Streptococcus pneumoniae. While there is still no licensed vaccine against Group A Streptococcus (GAS), there has been significant progress in the development of candidate vaccines in recent years. Read more

Supervisor: Dr A Shaw

19 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

Molecular mechanism of vimentin induced epithelial mesenchymal transition (EMT) and stemness in cancer cells

Queen Mary University of London Institute of Dentistry

Background. Most cancers are epithelial in origin and arise from a single progenitor cell, similar to an embryo, to become a clone of cells. Read more

Supervisors: Prof A Waseem, Dr H Tummala, Dr F Flores-Borja

Year round applications PhD Research Project Self-Funded PhD Students Only

Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute

Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more

Supervisors: Dr M Secrier, Dr L Cottone

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Chromatin remodelling complexes in human brain development

King’s College London Faculty of Life Sciences & Medicine

Chromatin regulators are a group of proteins that control the way the rest of the genome is opened up and “read” by the cellular machinery, with fundamental roles in development and disease. Read more

Supervisors: Dr CD Dias, Dr JA Atherton

Year round applications PhD Research Project Self-Funded PhD Students Only

Understanding the soil microbiome under controlled light conditions

University of Greenwich Faculty of Engineering and Science

Our research group is working within a consortium that is testing semi-transparent solar installations on crop growth-houses, to enhance biological and financial resilience in protected farming. Read more

Supervisors: Dr C.V.S. Supamaniam, Dr E Thompson

24 June 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Investigating the role of thymosin beta 10 in feline chronic kidney disease

Royal Veterinary College Central

Chronic kidney disease is an extremely common but heterogeneous condition in cats that adversely affects their health and welfare and is the most frequent cause of death in cats over five years of age. Read more

Supervisors: Dr E Vasilopoulou, Prof J Elliott, Dr R Jepson

28 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

Investigating the neuro-stromal-immune interactions in inflammageing and osteoarthritis.

University of Greenwich School of Pharmacy (Medway Campus)

Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) including osteoarthritis. Age-associated chronic low-grade inflammation (inflammageing) is a hallmark of osteoarthritis. Read more

Supervisor: Dr S Ashraf

Year round applications PhD Research Project Self-Funded PhD Students Only

Evaluating the role of immune microenvironment on cancer progression using spatial and imaging approaches

King’s College London School of Cancer and Pharmaceutical Sciences

Talented and motivated students, passionate about doing research and advancing cancer research, are invited to apply for this PhD position. Read more

Supervisor: Dr H Sailem

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

Possible role of mutant vimentin in cancer progression and metastasis

Queen Mary University of London Institute of Dentistry

Background. This project will investigate the role of the cytoskeletal protein vimentin in cancer progression and metastasis using cell and molecular biology approaches. Read more

Supervisors: Prof A Waseem, Dr F Flores-Borja, Dr H Tummala

Year round applications PhD Research Project Self-Funded PhD Students Only

Transcriptome biomarkers and mechanisms of chemoresistance

Queen Mary University of London Institute of Dentistry

Project Summary. This project aims to identify biomarkers linked to the most potent multimodal anticancer therapy with the least toxicity to counteract hemoresistance in head and neck squamous cell carcinoma (HNSCC). Read more

Supervisor: Dr M T Teh

Year round applications PhD Research Project Self-Funded PhD Students Only

Last chance to apply

Investigating the effect of promoters on gene expression in novel adeno-associated virus (AAV) producer cell lines.

Medicines and Healthcare Products Regulatory Agency Biotherapeutics and Advanced Therapies Team

We are seeking an enthusiastic candidate to work on an exciting and highly collaborative research project, aimed at identifying and characterising optimal promoter sequences to control expression of AAV genes to engineer novel stable AAV producer cell banks. Read more

Supervisor: Dr C Kerridge

19 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

Last chance to apply

Impact of adeono-associated virus (AAV) formulation on utility

Medicines and Healthcare Products Regulatory Agency Vaccines team

AAV gene therapy clinical trials are expanding to address unmet medical needs and the breadth of diseases to which AAVs are applied is increasing rapidly with over 200 trials registered globally. Read more

Supervisor: Dr S Kempster

19 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

Developing a novel drug screening platform for schistosomes using the free-living flatworm Schmidtea mediterranea

Kingston University Faculty of Health, Science, Social Care and Education

Schistosoma mansoni is one of three major schistosome species that infect over 240 million people across 70 developing countries, with an additional 0.6 billion at risk of infection. Read more

Supervisor: Dr E Shakir

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

Transcriptome homeostasis in cellular ageing and cancer

Queen Mary University of London Institute of Dentistry

Project Summary. We have previously established the oncogenic mechanisms of the transcription factor FOXM1 in perturbation of genome stability (1, 2), epigenome (3, 4) and adult progenitor epithelial stem cell proliferation (5). Read more

Supervisor: Dr M T Teh

Year round applications PhD Research Project Self-Funded PhD Students Only

An investigation on the association of high risk human papillomavirus (HPV) types with colonic adenomata and adenocarcinomas: a UK population based study

Kingston University Faculty of Health, Science, Social Care and Education

This PhD studentship invites application for a study “investigating the association between high risk human papillomavirus (HPV) types and colonic adenomata and adenocarcinomas in a UK population”. Colorectal cancer (CRC) is an important public health problem worldwide occupying most frequent causes of cancer-related mortality. Read more

Supervisor: Dr H Ashrafi

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

Development of a novel automatised platform for drug discovery in relevant human tissue models

University College London UCL Great Ormond Street Institute of Child Health

A 4-year funded PhD studentship is available in the UCL GOS Institute of Child Health “Developmental Biology and Cancer” department. Read more

Supervisors: Dr D Stoyanov, Prof P De Coppi, Dr GGG Giobbe

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

SLS SF3: PhD in Pharmacological intervention of ion channels for the treatment of cardiac disease

University of Westminster School of Life Sciences

Within our lab we study human ion channels, mainly potassium channels, that contain genetic mutations which lead to disease states. Read more

Supervisors: Dr KP Cunningham, Dr S Getting, Dr DG Gaze

17 May 2024 PhD Research Project Self-Funded PhD Students Only

Treating Glioblastoma: Tricyclic antidepressants repositioned and administered as a cancer therapy by a novel nanoparticle delivery system in vitro

Kingston University Faculty of Health, Science, Social Care and Education

Cancer is a disease that is rapidly increasing. The initiation and progression of cancer is a central topic of countless research with discoveries of multiple pathways implicated in formation and advancement of this debilitating disease. Read more

Supervisor: Dr A Elbediwy

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

The effect of antihypertensive drugs in the treatment of breast cancer as monotherapy and in combination with Nigella sativa

Kingston University Faculty of Health, Science, Social Care and Education

Cancer research is one of the most highly funded and research-intensive fields in laboratories. Read more

Supervisor: Dr N. W Wehida

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

Curing disease: using natural or novel compounds to target key signalling pathways

Kingston University Faculty of Health, Science, Social Care and Education

The role of signalling pathways in the initiation and progression of disease is an extensively studied but not clearly understood field. Read more

Supervisor: Dr A Elbediwy

Year round applications PhD Research Project Self-Funded PhD Students Only

The Impact of vitamin D supplementation on Wnt activity in the development of periodontitis

King’s College London Centre for Oral Clinical Translational Sciences

Vitamin D deficiency is a widespread problem in the UK. Vitamin D plays a protective role against a myriad of chronic diseases. Periodontal disease is the number one cause of tooth loss in the UK. Read more

Supervisors: Dr E Lu, Dr Jonathan P Richardson

Year round applications PhD Research Project Self-Funded PhD Students Only

Health and development outcomes and their interaction for children with chronic liver disease: a population-based cohort using novel linkage between health and education records

Great Ormond Street Hospital for Children NHS Trust GOSH BRC Applied Child Health Informatics Theme (Non-Clinical) PhD Studentships

Each year in the UK, 400 children are diagnosed with chronic liver disease (CLD), with a fifth requiring liver transplantation at some stage. Read more

Supervisors: Prof KH Harron, Dr AZ Zylbersztejn

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Understanding novel aspects of the phage infection process in WHO Critical pathogens using bacterial impedance cytometry

UK Health Security Agency Public Health

Clinicians are increasingly working with a limited range of antibiotics, which are becoming less effective as many bacteria develop resistance to them. Read more

Supervisor: Dr L Bock

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Dissecting behaviourally relevant feedback microcircuits in the brain

Queen Mary University of London Blizard Institute

Interactions between distinct neural circuits in the brain help in sensory-guided perceptual decisions. We have recently reported that task/context-switching behaviour is dependent upon specific populations of neurons in the frontal cortex which encode and convey rule-related information (Banerjee et al. Read more

Supervisor: Prof A.B Banerjee

10 May 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

Investigate the role of NHSL1 in vesicle trafficking and receptor recycling promoting cancer cell invasion using CRISPR-Cas9, microfluidics, and advanced live cell imaging.

King’s College London Health Schools

Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. Metastasis is the primary cause of cancer related deaths. Read more

Supervisor: Dr M Krause

Year round applications PhD Research Project Self-Funded PhD Students Only

The role of GLUT transporters in microglial metabolism, investigating functionality, regulation and drug targetable properties.

Kingston University Faculty of Health, Science, Social Care and Education

Modifying the brain’s metabolism as an intervention or for the treatment of Alzheimer’s disease represents a novel strategy for targeting what is recognised as a multifactorial condition which lacks effective therapeutic options. . Read more

Supervisor: Dr M Stolinski

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

Identifying Mechanisms of Tyrosine Kinase Inhibitor Resistance in Breast/Cervical Cancer (with emphasis on FGFR)

Kingston University Faculty of Health, Science, Social Care and Education

FGF signalling is implicated in cancer (e.g., breast and cervical cancer) susceptibility and progression, suggesting that this powerful developmental pathway is co-opted by cancer cells. Read more

Supervisor: Dr A Chioni

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

Selection and evaluation of new universal influenza vaccine candidates using monoclonal antibodies and digitally designed HA and NA libraries & pseudotype virus screens

University of Greenwich School of Pharmacy (Medway Campus)

Universal influenza vaccines are a major global R&D vaccine priority. The Temperton (ORCID. Read more

Supervisors: Dr N Temperton, Dr S Scott, Prof J Heeney

Year round applications PhD Research Project Self-Funded PhD Students Only

Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

University of Greenwich School of Pharmacy (Medway Campus)

The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more

Supervisors: Dr F Papagiannouli, Dr G Lall

Year round applications PhD Research Project Self-Funded PhD Students Only

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