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We have 24 Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Nottingham

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Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Nottingham

We have 24 Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Nottingham

Nottingham Trent University

Nottingham Trent University is a research centre of excellence

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University of Nottingham

Research that changes lives and shapes the future

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Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks

Nottingham Trent University School of Science & Technology
The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children. Read more
 Supervisor: Dr A Antonysunil
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring the molecular mechanisms of skin aging process and understanding the relationship between skin aging and systemic aging

University of Nottingham School of Pharmacy
Applicants are invited for fully funded 3 years full time PhD studentships, starting from 1st February 2023, or 1st April 2023, or 1st October 2023 at latest, based in the School of Pharmacy, The University of Nottingham. Read more
 Supervisor: Dr Z Zhu
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Providing insights into the molecular understanding of heart development and the formation of congenital heart defects.

University of Nottingham School of Life Sciences
Our research aim is to understand how the heart develops and then how it goes wrong to give rise to congenital heart defects (CHDs). Read more
 Supervisors: Dr S Loughna, Prof J D Brook
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of calcium signalling in regulating of tumour cell behaviour

University of Nottingham School of Life Sciences
Metastasis is the major cause of mortality in human cancers, yet we know relatively little of the fundamental biology that underlies the important transition to invasive malignancy. Read more
 Supervisors: Dr M Georgiou, Dr IM Maiellaro
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Overcoming replication stress–defining new mechanism from archaea to human

University of Nottingham School of Life Sciences
How cells respond to DNA replication stresses (e.g., DNA replication collapse, stalling or hyper-activity) is critical for their survival, and is a hallmark of cancers. Read more
 Supervisors: Dr E Bolt, Prof T Allers
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How to build and maintain a 3-dimensional polarised epithelial sheet

University of Nottingham School of Life Sciences
We are interested in how cells maintain normal cell shape within an epithelium. Correct epithelial cell shape is essential to maintain tissue integrity and when deregulated can cause diseases such as malignant cancers, diabetes, inflammation, and aging. Read more
 Supervisor: Dr M Georgiou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy
Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more
 Supervisor: Dr G S Winkler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Epigenomic transcriptomic mechanisms underlying human neuropsychiatric and neurodegenerative diseases

University of Nottingham School of Life Sciences
This project aims to use high throughput sequencing technologies and molecular approaches to understand how RNA epitranscriptomic processes contribute to susceptibility to human disorders of the brain. Read more
 Supervisor: Dr HM Knight
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exosome biogenesis and organelle trafficking in neurodegeneration.

University of Nottingham School of Life Sciences
Scientific summary. Intracellular transport pathways are fundamental for cell structure and function. Due to their longevity, complex morphology (long axonal and dendritic extensions) and requirement to maintain synaptic transmission, neurons are heavily dependent upon intracellular transport. Read more
 Supervisors: Dr A Hume, Dr DS Scott, Dr F Dajas-Bailador
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The use of Drosophila melanogaster to identify novel therapeutic agents for Alzheimer’s disease

University of Nottingham School of Life Sciences
Since 2003, our understanding of the causes of Alzheimer’s disease (AD) have improved considerably, however, in that time only one new drug treatment has been approved. Read more
 Supervisors: Dr M Georgiou, Dr Z Zhu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Optimising novel pre- and rehabilitation strategies to improve the physiological resilience of older surgical patients

University of Nottingham School of Life Sciences
PhD Description. In addition to rehabilitation, which has long been employed as method to enhance recovery from clinical stress events, there is burgeoning clinical and research interest in prehabilitation, an approach employed to prepare individuals for these events. Read more
 Supervisor: Dr B Phillips
 22 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Exploring the multi-organ benefits of Rapamune in relation to ageing physiology

University of Nottingham School of Life Sciences
PhD Description. Drug repurposing is an emerging avenue of research in the field of Geroscience; a field whose stated aim is to “accelerate research into the basic mechanisms driving ageing which could lead to improved clinical interventions”. Read more
 Supervisor: Prof P Atherton
 22 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Exploring the role of habitual physical activity in driving physiological ageing

University of Nottingham School of Life Sciences
PhD Description. Robust evidence regarding the biological mechanisms responsible for the health benefits of physical activity, and the detrimental impacts of inactivity is lacking. Read more
 Supervisor: Prof P Greenhaff
 22 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Developmental consequences of heat stress during early mammalian embryogenesis

University of Nottingham School of Biosciences
Epidemiological evidence in humans indicates that acute heat exposure around the time of mating results in pregnancy loss, with potential long-term consequences for offspring health and wellbeing; although these latter adverse effects are poorly understood. Read more
 Supervisors: Prof K D Sinclair, Dr R Alberio, Prof D Gardner
 10 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

University of Nottingham School of Medicine
Implanted medical devices are crucial in healthcare, valued at around £400 billion globally, however there is a high failure rate, often due to the foreign body reaction, where a fibrotic capsule forms around the implant with associated inflammation, loosening and infection. Read more
 Supervisors: Prof M Alexander, Prof AG Ghaemmaghami, Dr D H Kim, Prof BO Ollivere
 30 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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