Molecular Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Sheffield

University of Sheffield Department of Chemical & Biological Engineering

Microalgal Biorefineries

A major contemporary challenge in industrial manufacturing is the development of sustainable production processes. This includes reduced resource consumption and CO2 generation, and energy efficient operations with maximised product outputs. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Sheffield Department of Chemical & Biological Engineering

Genomic and Proteomics-Based Characterisation of Microalgal Cell Factories

Microalgae have generated increasing interest as microbial cell factories to produce proteins, pigments, therapeutics, and nutraceuticals. Read more

Supervisors: Dr J Pandhal, Prof MJ Dickman

Year round applications PhD Research Project Self-Funded PhD Students Only

Molecular characterisation of scavenger receptor ligand binding.

Supervisors: Dr S Brown, Dr I Evans

Scavenger receptors have been identified as being important in Human disease and normal physiological responses. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Identification of the molecular pathways that guide tissue regeneration

Year round applications PhD Research Project Self-Funded PhD Students Only

The study of regenerative biology aims to elucidate the innate ability of organisms to replace tissues or organs after they have been removed or damaged. Read more

Supervisor: Dr H Roehl

University of Sheffield Department of Chemical & Biological Engineering

Glycosylation in Microalgal Host Cells

Microalgae have generated increasing interest as microbial cell factories to produce therapeutics proteins. This is because they can grow on very cheap media and their GRAS (generally regarded as safe) status means they are a fantastic option for the production of therapeutics that can be administered orally. Read more

Supervisors: Dr J Pandhal, Dr C Evans

Year round applications PhD Research Project Self-Funded PhD Students Only

Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

Year round applications PhD Research Project Self-Funded PhD Students Only

Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more

Supervisor: Dr C Guo

Control of skeletal muscle regeneration and aging by cell signalling

Supervisor: Dr A G Borycki

The ability of skeletal muscles to regenerate in response to injury, exercise, growth or disease depends on a population of adult skeletal muscle stem cells. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Sheffield Department of Chemical & Biological Engineering

Engineering Virus-Like Particles for Next-Generation Vaccine Manufacturing

Virus-like particles (VLPs) are structures typically composed of viral structural proteins that self-assemble into virus-like structures. Read more

Supervisors: Dr K Tee, Prof TS Wong, Dr C Evans

30 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

University of Sheffield School of Medicine and Population Health

Antisense technologies as potential treatments for Cushing’s disease

Cushing’s disease is a devastating condition caused by a pituitary corticotroph tumour that over-expresses the proopiomelanocortin gene (POMC) and secretes high levels of ACTH. Read more

Supervisor: Dr E H Kemp

Year round applications PhD Research Project Self-Funded PhD Students Only

The regulation of scavenger receptors in cancer

Supervisors: Dr S Brown, Dr C Guo

The expression of some scavenger receptors has been identified as being poor for cancer prognosis. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously in the Human body. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Sheffield Department of Chemical & Biological Engineering

Microalgal Carbon Sequestration Towards a Carbon Negative Economy

The increasing CO2 emissions to the atmosphere is a major environmental crisis that is in immediate need of innovative solutions. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Sheffield Department of Chemical & Biological Engineering

Algal Bioplastics

Single use plastic is a major environmental concern that is urgently in need of innovative solutions. Microalgae are photosynthetic organisms that can be employed to develop processes that are environmentally sustainable. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Sheffield Department of Chemical & Biological Engineering

Algae Feedstock for Food Security

There is an urgent need to find innovative and sustainable solutions to meet the demands of feeding the growing global population. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Sheffield Department of Chemical & Biological Engineering

Algae Feedstock for Energy Security

A major challenge in contemporary energy and environmental management is to develop processes for food and energy security that are environmentally sustainable. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only