University of Dundee Molecular Biology PhD Projects, Programmes & Scholarships

We have 38 University of Dundee Molecular Biology PhD Projects, Programmes & Scholarships

Investigating mechanisms of extra-cellular matrix remodelling and fibrosis in the gastrointestinal tract

Inflammatory bowel diseases, such as Crohn's disease, are increasing in prevalence globally. These are caused by chronic inflammation in the gut, there is no cure and medications are not effective for all. Read more

Supervisor: Dr M Mclean

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Utility of in silico prediction tools to aid variant interpretation

University of Dundee School of Medicine

Accurate variant interpretation represents is essential for the successful implementation of genetic testing in the clinical setting. Read more

Supervisor: Dr P Newey

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Speeding up the plant microbiota: investigating the impact of speed breeding on host-microbe interactions in the barley rhizosphere

University of Dundee School of Life Sciences

Feeding a growing world population amid climatic modifications and international conflicts represents an unprecedent challenge for crop production. Read more

Supervisors: Dr D Bulgarelli, Dr C Campoli

Year round applications PhD Research Project Self-Funded PhD Students Only

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BARIToNE: Improving barley climate resilience using a candidate gene approach (Project code 24H)

University of Dundee School of Life Sciences

Supervisors. Lead supervisor - Dr Martin Balcerowicz, University of Dundee. Second supervisor - Dr Craig Simpson, James Hutton Institute. Read more

Supervisors: Dr M Balcerowicz, Dr C Simpson, Ms G MacDonald

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular characterisation of post-tuberculous bronchiectasis

University of Dundee School of Medicine

Tuberculosis is a major health problem is Iraq and globally. While treatment of TB, including MDR TB has greatly improved resulting in high rates of clinical cure, many patients with TB are left with persisting lung disease including airflow obstruction and bronchiectasis. Read more

Supervisors: Prof J Chalmers, Dr M Al-Khairalla

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

University of Dundee School of Medicine

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Supervisors: Dr L Kang, Dr C Murdoch

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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PI3K-Akt expression in dysplastic oral lesions and implications for recurrence and malignant transformation

University of Dundee Dental School

There are around 12,400 new head and neck cancer cases in the UK every year, that's 34 every day (2016-2018) with 4,143 deaths each year. Read more

Supervisors: Prof M Macluskey, Dr I Ellis, Dr M Islam, Dr S. J. Jones

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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MSc by Research: The Generation Gap – understanding tissue communication during grain development

University of Dundee School of Life Sciences

Cereal grain provides more calories than any other source to our diet, making grain production vital to food security. We study grain development in barley, a globally important cereal, and a powerful genetic model system. Read more

Supervisor: Dr S McKim

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Investigation of the interplay between the cell cycle and Notch intracellular domain levels in presomitic mesoderm cells in somitogenesis

University of Dundee School of Life Sciences

One of the key processes in embryo development is somitogenesis. This is the formation of segments, known as somites, that go on to develop into bone and skeletal muscle. Read more

Supervisor: Prof J K Dale

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Function of presomitic mesoderm specific phosphorylation of the Notch intracellular domain in somitogenesis

University of Dundee School of Life Sciences

The Notch signalling pathway is one of the key pathways required for the developing embryo. It is especially important for the process of somitogenesis, the formation of body segments that develop into e.g. Read more

Supervisor: Prof J K Dale

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: m6A modification of segmentation clock mRNAs and its role in somitogenesis

University of Dundee School of Life Sciences

During early embryogenesis, segments (somites) are formed during a process called somitogenesis. These somites will go on to form the bones and muscles of the skeleton. Read more

Supervisors: Prof J K Dale, Dr P Murray

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Degrade or die: Understanding proteasome regulation upon stress

University of Dundee School of Life Sciences

The Rousseau lab is interested in decoding how protein degradation by the proteasome is regulated in cells so that accumulation of unfolded, misfolded, or damaged proteins can be cleared before they become deleterious. Read more

Supervisor: Dr A Rousseau

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Nutrient-dependent regulation of microglia function and immune responses

University of Dundee School of Life Sciences

Microglia are constantly sensing the brain environment for metabolic changes, damage and pathogenic invasion. Microglia are highly metabolically active, with activation in response to inflammatory stimulation increasing glycolytic demand. Read more

Supervisors: Dr A Lloyd, Dr L Sinclair

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Resolving immune cell proteomes to subcellular resolution

University of Dundee School of Life Sciences

Immune activation triggers dramatic proteome remodelling. Using high sensitivity mass spectrometry we have mapped immune cell proteomes, providing novel insights into immune cell phenotypes and revealing the metabolic and protein synthesis machinery and environmental sensors that shape cell fate. Read more

Supervisor: Dr A Howden

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 38 University of Dundee Molecular Biology PhD Projects, Programmes & Scholarships

University of Dundee Molecular Biology PhD Projects, Programmes & Scholarships

We have 38 University of Dundee Molecular Biology PhD Projects, Programmes & Scholarships

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