Molecular Biology (b) PhD Projects, Programmes & Scholarships

We have 39 Molecular Biology (b) PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The University of Manchester Faculty of Biology, Medicine and Health

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

Supervisors: Dr MM Mennon, Prof MH Buch

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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ROLE OF FOXO1 TRANSCRIPTION FACTOR IN B-CELL MALIGNANCIES

Masaryk University Faculty of Medicine

The project is focused on FoxO1 transcription factor and its role in the pathophysiology of chronic lymphocytic leukemia (CLL). Although the therapy of CLL has made several remarkable improvements, the disease still remains incurable. Read more

Supervisor: Assoc Prof Marek Mraz

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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A miRNA taming floral homeotic genes

Max Planck Institute for Chemical Ecology International Max Planck Research School

Background. The floral structure significantly influences the interaction of angiosperms with their environment, not least because it defines the set of species by which plants are pollinated. Read more

Supervisors: Prof G Theißen, Dr L Gramzow, Prof J Gershenzon

18 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Haematology: Oncogenic mechanisms causing malignant transformation of B cells and plasma cells

University of Leeds Faculty of Medicine and Health

Cancers of B cells and plasma cells, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Read more

Supervisor: Prof U Klein

Year round applications PhD Research Project Self-Funded PhD Students Only

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REGULATION OF BCR SIGNALLING BY DNA DAMAGE RESPONSE AND P53 PROTEIN

Masaryk University Faculty of Medicine

Doctoral study program. Molecular Medicine. Research area. Cancer biology. Consultant. Marek Mraz, MD, Ph.D. We are looking for a motivated PhD student that would like to work on the following project funded by the ERC (European Research Council) Starting grant. Read more

Supervisor: Dr MB Boudny

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Role of BTG1 and BTG2 in acute lymphocytic leukaemia and diffuse large B-cell lymphoma

University of Nottingham School of Pharmacy

Acute lymphocytic leukaemia (ALL) and diffuse large B-cell lymphoma (DLBCL) is often associated with small deletions of or point mutations in the highly related BTG1 or BTG2 genes. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Creation of cell lines modelling complex karyotype in B cell lymphomas using CRISPR/Cas9

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Chronic lymphocytic leukaemia (CLL) and diffuse large B cell lymphoma (DLBCL) make up more than half of all the newly diagnosed cases of non-Hodgkin’s lymphoma (NHL), the 6th most common cancer in the UK. Read more

Supervisors: Dr J Slupsky, Dr N Kalakonda, Dr M Glenn

1 May 2024 PhD Research Project Self-Funded PhD Students Only

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Design and Folding of beta barrel membrane proteins

University of Leeds Faculty of Biological Sciences

The cell walls of Gram negative bacteria are packed with b-barrel outer membrane proteins (OMPs) whose function are essential for bacterial growth and virulence. Read more

Supervisors: Prof S E Radford, Prof D B Brockwell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics

Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more

Supervisor: Dr RB Burton

1 July 2024 PhD Research Project Self-Funded PhD Students Only

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Genetics of flowering shoot temperature responses in plants

Durham University Department of Biosciences

The shape of plants is shaped by both genetics and environment; changes in response to temperature can be the most dramatic of all. Read more

Supervisor: Dr J Hepworth

3 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences

Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more

Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Unravelling the Intricacies of Stress Hormone Regulation

University of Reading Department of Biomedical Sciences

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

Supervisor: Dr A B Bicknell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating Neuropeptide Signalling From Synthesis to Survival

University of Reading Department of Biomedical Sciences

Neuropeptides, comprising of short amino acid chains, are potent bioactive molecules with extensive neuromodulatory functions and are predominantly expressed within the central nervous system. Read more

Supervisors: Dr A B Bicknell, Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

University of Leicester Molecular and Cell Biology

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

Supervisor: Dr G Hall

Year round applications PhD Research Project Self-Funded PhD Students Only

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