Molecular Biology (disorder) PhD Projects, Programmes & Scholarships

Precision Therapy for NBAS-related disorder

University of Sheffield School of Medicine and Population Health

It is very well recognised that rare diseases offer the potential to uncover new information about mechanisms underlying a range of phenotypes. Read more

Supervisor: Dr M Balasubramanian

Year round applications PhD Research Project Self-Funded PhD Students Only

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Reward processing deficits in the cacna1c rat model of genetic risk for psychiatric disorder: biological bases and potential pharmacological rescue.

Cardiff University Cardiff School of Medicine

Hodge Centre for Translational Neuroscience. “Towards innovative treatments for mental illness”. Cardiff University Neuroscience and Mental Health Innovation Institute. Read more

Supervisor: Prof D Dwyer

7 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Self funded MSc by Research or PhD in Biology: Delineating neuronal structure and function in the autism spectrum disorder neurofibromatosis type 1

University of York Department of Biology

Neurofibromatosis type 1 (NF1) is among the most common monogenetic disorders of humans and patients show a high prevalence of Autism Spectrum Disorders. Read more

Supervisors: Dr I Hahn, Dr W Brackenbury

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Understanding how mutations in the kinase TLK2 cause a neurodevelopmental disorder

University of York York Biomedical Research Institute

Tousled-like kinase 2 (TLK2) was recently identified as a novel genetic locus for a neurodevelopmental disorder. Patients predominantly possess de novo mutations in TLK2, leading to a reduction in its expression or kinase activity. Read more

Supervisors: Dr G Evans, Dr I Hahn

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identification of transcriptomic signatures of autism-like neurodevelopmental disorder

The University of Manchester Faculty of Biology, Medicine and Health

The overarching aim of this project is to define transcriptional patterns and identify new genetic elements essential for the correct development of the human brain. Read more

Supervisors: Dr PG Grzechnik, Dr A J Whitmarsh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genetic causes of novel neurodevelopmental disorders

University of Otago Department of Biochemistry

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Supervisor: Assoc Prof L Bicknell

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Exploring a novel neurodevelopmental disease gene using a zebrafish model

University of Otago Department of Biochemistry

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Supervisor: Assoc Prof L Bicknell

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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The Rhonski project: Examining Rho and Notch signalling in skin development and disease

St George’s, University of London Medical and Biomedical Education Institute

The skin provides a crucial protective layer between the human body and the outside world. Whilst the epidermis forms a barrier against infection, the inner dermis houses the blood vessels required to sustain the hair follicles and cells contained within both the epidermal and dermal layers. Read more

Supervisors: Dr LS Southgate, Dr A Chikh

26 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Pharmacology of ion channels in human genetic disorders

University of Leeds Faculty of Biological Sciences

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisors: Dr J D Lippiat, Dr S Clapcote, Dr K Simmons, Dr S Muench

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of extracellular vesicles and intercellular signalling in inherited kidney cancer

Cardiff University Cardiff School of Medicine

This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£60,000 total). Read more

Supervisor: Dr E Dunlop

31 May 2024 PhD Research Project Self-Funded PhD Students Only

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Study of early pathological changes in calcified cartilage in osteoarthritis and alkaptonuria

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

We are seeking a motivated individual to work on this exciting project investigating the role that the calcified cartilage has in rare and common joint osteoarthritis, using novel approaches such as gene silencing and establishment of a 3D chondrocyte cell culture model. Read more

Supervisor: Dr JH Hughes

10 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating the role of oxidative metabolites in joint destruction in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences

We are seeking a motivated researcher to work on a pioneering project investigating the role of oxidative stress in alkaptonuria (AKU) and associated conditions. Read more

Supervisors: Dr BN Norman, Dr JH Hughes, Prof G Bou-Gharios

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the cellular functions of Trappc9 in brain development and microcephaly

University of Liverpool Institute of Systems, Molecular and Integrative Biology

This PhD project will investigate the cellular functions of the Trafficking protein particle complex subunit 9 (Trappc9) and its roles in brain development. Read more

Supervisors: Dr A Plagge, Dr T Zech

Year round applications PhD Research Project Self-Funded PhD Students Only

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Transcriptional kinases in cancer and developmental disorders

University of Leicester Molecular and Cell Biology

Cyclin-dependent kinases (CDKs) are protein kinases performing essential functions in regulation of cell cycle and transcription. Read more

Supervisor: Dr MT Tellier

Year round applications PhD Research Project Self-Funded PhD Students Only

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Effect of androgens on preantral follicle development

University of Sheffield School of Medicine and Population Health

Polycystic ovary syndrome (PCOS) is a condition that affects >5% of women of reproductive age and is the most common cause of menstrual dysfunction and is associated with metabolic abnormalities and increased risk to long-term health. Read more

Supervisors: Dr M Fenwick, Dr N Krone

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 18 Molecular Biology (disorder) PhD Projects, Programmes & Scholarships

Molecular Biology (disorder) PhD Projects, Programmes & Scholarships

We have 18 Molecular Biology (disorder) PhD Projects, Programmes & Scholarships

Precision Therapy for NBAS-related disorder

Reward processing deficits in the cacna1c rat model of genetic risk for psychiatric disorder: biological bases and potential pharmacological rescue.

Self funded MSc by Research or PhD in Biology: Delineating neuronal structure and function in the autism spectrum disorder neurofibromatosis type 1

Understanding how mutations in the kinase TLK2 cause a neurodevelopmental disorder

Identification of transcriptomic signatures of autism-like neurodevelopmental disorder

Genetic causes of novel neurodevelopmental disorders

Exploring a novel neurodevelopmental disease gene using a zebrafish model

The Rhonski project: Examining Rho and Notch signalling in skin development and disease

Pharmacology of ion channels in human genetic disorders

The role of extracellular vesicles and intercellular signalling in inherited kidney cancer

Study of early pathological changes in calcified cartilage in osteoarthritis and alkaptonuria

Investigating the role of oxidative metabolites in joint destruction in osteoarthritis

Investigating the cellular functions of Trappc9 in brain development and microcephaly

Transcriptional kinases in cancer and developmental disorders

Effect of androgens on preantral follicle development

We have 18 Molecular Biology (disorder) PhD Projects, Programmes & Scholarships

Molecular Biology (disorder) PhD Projects, Programmes & Scholarships

We have 18 Molecular Biology (disorder) PhD Projects, Programmes & Scholarships

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