Molecular Biology (enzymes) PhD Projects, Programmes & Scholarships

We have 35 Molecular Biology (enzymes) PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Novel glycoprotease discovery and characterisation for enhanced detergent performance

Newcastle University BiSCoP CTP

In this exciting joint academia-industry project the student will exploit metagenomes and the huge untapped capacity of the human gut microbiota to breakdown glycoconjugates to discover novel protease enzymes that can potentially increase the performance and environmental sustainability of leading P&G automatic dishwashing brands. Read more

Supervisors: Dr E Lowe, Dr D Bolam, Dr AL Morales Garcia, Mrs K Bell-Rusiewicz

2 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Developing novel targeted therapeutic approaches through induced-proximity of proteins

University of Dundee School of Life Sciences

Protein post-translational code is at the heart of protein function and signal transduction in cells. Enzymes catalyse the addition or removal of post-translational modifications (PTM), such as phosphorylation, methylation, acetylation, and ubiquitylation, on proteins. Read more

Supervisors: Prof G Sapkota, Prof A Ciulli

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Protein engineering enzymes for Industry

University of Reading Department of Biomedical Sciences

Project Overview. We are interested in key features of the protein sequence - structure - function relationship, and how this information can be translated to health. Read more

Supervisor: Prof K A Watson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Disrupting Oral Biofilm Formation & Maturation: Covalently Inhibiting Glucan Sucrases from Streptococci

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team: Dr Seung Lee (School of Chemistry), Prof. Jeremy Webb (School of Biological Sciences and National Biofilms Innovation Centre), Prof. Read more

Supervisor: Dr SS Lee

31 August 2024 PhD Research Project Competition Funded PhD Project (European/UK Students Only)

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Covalent inhibition of streptococcal glucan sucrases to disrupt oral biofilm development

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team: Dr Seung Lee (School of Chemistry), Prof. Jeremy Webb (School of Biological Sciences and national Biofilms Innovation Centre), Prof. Read more

Supervisor: Dr SS Lee

31 August 2024 PhD Research Project Competition Funded PhD Project (European/UK Students Only)

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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Translating protection of cell-surface receptor LRP1 into potential disease-modifying therapies for osteoarthritis.

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Osteoarthritis (OA) causes pain and disability and is the most prevalent age-related joint disorder worldwide but there are no disease-modifying drugs available. Read more

Supervisors: Dr K Yamamoto, Prof G Bou-Gharios

Year round applications PhD Research Project Self-Funded PhD Students Only

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Mechanisms controlling gene expression in hypoxia and inflammation

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Oxygen is one of the most important molecules for life. Every member of the animal kingdom depends on oxygen to help metabolize its food and drive many critical processes in metabolism. Read more

Supervisor: Prof S Rocha

Year round applications PhD Research Project Self-Funded PhD Students Only

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Evaluating the impact of genotoxic aldehyde stress in premature ageing

University of Leicester Department of Chemistry

Aldehydes are highly reactive chemicals that are common pollutants and human metabolites. However, the vast majority of aldehydes’ biological functions are unknown. Read more

Supervisors: Dr R Hopkinson, Dr K Tanaka

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders

University of Leeds Faculty of Biological Sciences

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Prof I Wood

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded PhD- Understanding the molecular mechanism of a bacterial genome defence system and its synergy with CRISPR-Cas

University of Bristol School of Biochemistry

Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well-studied of which are the Restriction-Modification and the CRISPR-Cas enzymes. Read more

Supervisor: Prof M D Szczelkun

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self funded MSc by research or PhD in Biology: Discovery, evolution and applications in plant natural product biosynthesis

University of York Department of Biology

Lead supervisor: . The student will be registered with the Department of Biology. Plants are capable of producing complex molecules for defense and adaptation. Read more

Supervisor: Dr B R Lichman

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

The University of Manchester Department of Chemistry

Plastics are a broad range of solid polymeric materials that have found widespread application globally. However, there has been a steady accumulation of discarded plastics and there is now growing awareness that they present a significant hazard to the natural environment and human health. Read more

Supervisor: Dr L Wong

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 35 Molecular Biology (enzymes) PhD Projects, Programmes & Scholarships

Molecular Biology (enzymes) PhD Projects, Programmes & Scholarships

We have 35 Molecular Biology (enzymes) PhD Projects, Programmes & Scholarships

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