Molecular Biology (genetic) PhD Projects, Programmes & Scholarships

We have 140 Molecular Biology (genetic) PhD Projects, Programmes & Scholarships

The use of life course epidemiology to support the experimental characterisation of genetic variation

University of Bristol Bristol Medical School

Project Background. There has been a rapid expansion in the generation of genetic sequence data over the last decade. Understanding the potential relevance of genetic mutations to human health remains challenging. Read more

Supervisors: Prof N Timpson, Dr L Corbin, Dr BL Lam

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Identifying causal pathways to disease using DNA methylation predicted blood traits.

University of Bristol Bristol Medical School

Project Background. Blood cell types have been implicated in pathogenesis of chronic diseases. Genome wide association studies have identified thousands of variants associated with blood trait variation. Read more

Supervisors: Dr J Min, Dr E Hannon, Prof J MIll

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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The genetic map of human molecular phenotypes

University of Bristol Bristol Medical School

Rationale. Genome wide associations studies (GWASs) have discovered many genetic associations with a large range of human traits, but the functional consequences of GWAS signals often remain elusive, as most GWAS signals reside in non-coding genomic regions. Read more

Supervisors: Dr J Min, Dr G Hemani, Dr JH Hawe

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Evaluating the role of circulating proteins in cancer risk and progression using genetic and observational approaches

University of Bristol Bristol Medical School

Rationale. Circulating proteins play fundamental roles in biology and disease aetiology, including development of cancer, and are the direct targets of many drugs (1). Read more

Supervisors: Prof R Martin, Dr JY Yarmolinsky, Dr P Haycock

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Skeletal Muscle Organoid Models for Genetic Mitochondrial Disease (ref: SF22/HLS/APP/Johnson)

Northumbria University Faculty of Health and Life Sciences

Genetic mitochondrial diseases are both clinically and genetically heterogeneous. Read more

Supervisor: Dr S Johnson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

University of Leeds Faculty of Medicine and Health

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more

Supervisors: Prof P Hopkins, Dr M-A Shaw, Dr C Diggle

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the genetic basis of immunological overlap between inflammatory diseases

The University of Manchester Faculty of Biology, Medicine and Health

Genetic studies have identified numerous variants within the human genome associated with susceptibility to common complex inflammatory diseases, such as rheumatoid arthritis (RA) and ulcerative colitis (UC). Read more

Supervisors: Mr P Martin, Prof S Eyre, Prof A Morris

Year round applications PhD Research Project Self-Funded PhD Students Only

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Reward processing deficits in the cacna1c rat model of genetic risk for psychiatric disorder: biological bases and potential pharmacological rescue.

Cardiff University Cardiff School of Medicine

Hodge Centre for Translational Neuroscience. “Towards innovative treatments for mental illness”. Cardiff University Neuroscience and Mental Health Innovation Institute. Read more

Supervisor: Prof D Dwyer

7 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Genetic causes of novel neurodevelopmental disorders

University of Otago Department of Biochemistry

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Supervisor: Assoc Prof L Bicknell

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Leveraging Functional Genomics to Understand Mitonuclear Combinations in Leber Hereditary Optic Neuropathy (Ref: FFS24/HLS/APP/WINTER)

Northumbria University Faculty of Health and Life Sciences

Mitochondria are small structures present in every cell of our body, which convert the food we eat into an energy source that cells can use. Read more

Supervisors: Dr M Winter, Prof M Lako, Dr G Hilgen

25 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating the role of dietary fructose in the development of early-onset colorectal cancer

University of Bristol Bristol Medical School

Project Background. This project will investigate the role of fructose in the development of early-onset colorectal cancer (EOCRC) in adults <50 years. Read more

Supervisors: Dr E Vincent, Dr A Chambers, Dr R Richmond, Dr NM Murphy

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Pharmacology of ion channels in human genetic disorders

University of Leeds Faculty of Biological Sciences

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisors: Dr J D Lippiat, Dr S Clapcote, Dr K Simmons, Dr S Muench

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the genetic determinants of ultra-complex telomere fusion

Cardiff University Cardiff School of Medicine

We are seeking a motivated molecular biologist to study the mechanisms by which telomere dysfunction impacts cancer genomes. Read more

Supervisor: Prof D Baird

3 May 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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Breastfeeding and big babies - lifecourse and genomics epidemiological approaches to disentangle cause and effect.

University of Bristol Bristol Medical School

Rationale. The World Health Organisation recommends exclusively breastfeeding for 6 months, but in the UK, only 1% of infants meet the guidelines (1). Read more

Supervisors: Dr L Zuccolo, Dr LJ Johnson, Dr L Howe, Dr C Borges

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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