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We have 26 Molecular Biology (molecular modelling) PhD Projects, Programmes & Scholarships

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Molecular Biology (molecular modelling) PhD Projects, Programmes & Scholarships

We have 26 Molecular Biology (molecular modelling) PhD Projects, Programmes & Scholarships

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The genetic map of human molecular phenotypes

University of Bristol Bristol Medical School
Rationale. Genome wide associations studies (GWASs) have discovered many genetic associations with a large range of human traits, but the functional consequences of GWAS signals often remain elusive, as most GWAS signals reside in non-coding genomic regions. Read more
 Supervisors: Dr J Min, Dr G Hemani, Dr JH Hawe
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Maastricht University Cardiovascular Research Institute Maastricht (CARIM)
Applications can only be submitted via our website. The specific position for Doctoral Candidate 6 (DC6) in the consortium, which is part of Work Package 2 (WP2), aims. Read more
 Supervisor: Dr G Nicolaes
 30 April 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences
Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more
 Supervisors: Dr M Young, Dr J Parker
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Optimizing phage-antibiotic-synergies to kill bacterial pathogens

The University of Manchester Faculty of Biology, Medicine and Health
Phage therapy, the use of viruses that only infect bacterial cells and kill them, is a promising potential solution to the antimicrobial resistance crisis that is threatening modern medicine1. Read more
 Supervisors: Prof M Brockhurst, Dr CI Igler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Creation of cell lines modelling complex karyotype in B cell lymphomas using CRISPR/Cas9

University of Liverpool Institute of Systems, Molecular and Integrative Biology
Chronic lymphocytic leukaemia (CLL) and diffuse large B cell lymphoma (DLBCL) make up more than half of all the newly diagnosed cases of non-Hodgkin’s lymphoma (NHL), the 6th most common cancer in the UK. Read more
 Supervisors: Dr J Slupsky, Dr N Kalakonda, Dr M Glenn
 1 May 2024  PhD Research Project  Self-Funded PhD Students Only
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Discovery of novel antibiotics through synthesis of lab-based (biochem/microbio) and computational microbiology (molecular dynamics/deep generative learning/AI)

University of Portsmouth School of Pharmacy and Biomedical Sciences
As stated by the World Health Organisation (WHO), antimicrobial resistance (AMR) is one of the greatest public health threats facing humanity. Read more
 Supervisor: Dr R Draheim
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genetics of flowering shoot temperature responses in plants

Durham University Department of Biosciences
The shape of plants is shaped by both genetics and environment; changes in response to temperature can be the most dramatic of all. Read more
 Supervisor: Dr J Hepworth
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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The role of regulatory evolution in phage ecology

The University of Manchester Faculty of Biology, Medicine and Health
The regulation of genes crucially determines the fitness and function of all organisms. This is particularly relevant for bacteriophages, the viruses that infect bacteria, as they rely on a tightly scheduled program for a successful infection. Read more
 Supervisors: Dr M Lagator, Dr CI Igler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Building new nano-biosensors for healthcare: Linking biology to the world of carbon nanotechnology through synthetic biology

Cardiff University Cardiff School of Biosciences
Project Descriptions. Proteins are nature’s very own molecular machines carrying out functions ranging from catalysis to molecular recognition to energy conversion. Read more
 Supervisors: Prof D Jones, Dr M Palma, Dr WK Kelton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using genome engineering and bioinformatics to understand heterochromatin and centromere function in Schizosaccharomyces pombe and in cancer cells

University of Nottingham School of Life Sciences
Centromeres are the DNA sequences on eukaryotic chromosomes that mediate accurate chromosome segregation at both mitotic and meiotic cell divisions. Read more
 Supervisors: Dr W R A Brown, Dr W Wickstead
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Where has all of the carbon gone? Understanding the molecular mechanisms of long-term soil carbon capture

The University of Manchester Department of Earth and Environmental Sciences
Soils, while unglamorous, form the basis of the terrestrial biosphere and are ultimately the source of the majority of the food that we eat, yet fundamental aspects of how soils form and how they store carbon are poorly understood. Read more
 Supervisors: Prof D Cameron, Dr S Nixon
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Targeting ageing and neurodegenerative diseases using the fruit-fly Drosophila melanogaster

Royal Holloway, University of London School of Biological Sciences
In the last 20 years the fruit fly Drosophila melanogaster emerged as a pre-eminent model system for studying changes that occur during both normal and pathological ageing (~75 per cent of the genes that cause disease in humans are also found in the fruit fly!). Read more
 Supervisor: Dr H Augustin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How do prenatal steroids elevate autism likelihood?

University of Reading Department of Biomedical Sciences
The causes of autism remain unknown. Some literature has showed a link between higher levels of steroid hormones such as testosterone in the womb and autism in children, particularly males. Read more
 Supervisors: Dr N Vasudevan, Prof C Williams, Prof B Chakrabarti
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Systemic infections accelerate tau spreading by promoting glial activation

University of Southampton School of Biological Sciences
Alzheimer’s disease (AD) is a neurodegenerative disease, with a complex biology. In this PhD project, we aim to explore the cellular and molecular mechanisms underlying tau pathology. Read more
 Supervisor: Prof J Teeling
 17 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

The University of Manchester Department of Chemistry
Plastics are a broad range of solid polymeric materials that have found widespread application globally. However, there has been a steady accumulation of discarded plastics and there is now growing awareness that they present a significant hazard to the natural environment and human health. Read more
 Supervisor: Dr L Wong
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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