Molecular Biology (protein) PhD Projects, Programmes & Scholarships

We have 185 Molecular Biology (protein) PhD Projects, Programmes & Scholarships

Better together: constructing tuneable fluorescent protein sensors for cellular imaging of protein-protein interactions

Cardiff University Cardiff School of Biosciences

Project Description. Protein-protein interactions (PPIs) commonly occur in biology with ~650,000 contributing to processes critical to human life. Read more

Supervisors: Prof D Jones, Dr PD Watson, Dr G Menzies, Dr R Clarkson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Chaperones and the response to protein misfolding stress

The University of Manchester Faculty of Biology, Medicine and Health

Misfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they form aggregates that are sequestered to specific sites within cells. Read more

Supervisors: Prof C M Grant, Prof M Ashe

Year round applications PhD Research Project Self-Funded PhD Students Only

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Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies

University of Leicester Molecular and Cell Biology

Whether a cell dies or not has profound consequences on health and disease. In healthy tissue, cells that acquire high levels of genetic damage are safely removed via a process of programmed cell death. Read more

Supervisor: Dr JF Fox

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovering and characterising new protein antimicrobials

University of Reading Department of Biomedical Sciences

Antibiotic resistant infections are spreading globally and becoming a leading cause of death worldwide, already surpassing malaria and HIV. Read more

Supervisor: Dr C Sharp

Year round applications PhD Research Project Self-Funded PhD Students Only

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Membrane protein-metabolite interactions important in mitochondrial energy metabolism for burning fat as heat (CRICHTON_U24DTP)

University of East Anglia Norwich Medical School

Primary supervisor - Dr Paul Crichton . Secondary supervisor - Prof. Tom Clarke (UEA) . Mitochondria in our cells harness energy through the breakdown of nutrients to produce ATP through oxidative phosphorylation. Read more

Supervisor: Dr P Crichton

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Self-Navigating Nanocarriers for Intracellular Protein Delivery

Queen’s University Belfast School of Pharmacy

Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more

Supervisor: Dr W Al-Jamal

Year round applications PhD Research Project Self-Funded PhD Students Only

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Bioinformatics studies of protein structures, functions and their interactions

University of Reading Department of Biomedical Sciences

The computational study of protein structures, functions and their interactions is fundamental to our understanding of disease. Read more

Supervisor: Prof L J McGuffin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

University of Leicester Molecular and Cell Biology

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

Supervisor: Dr G Hall

Year round applications PhD Research Project Self-Funded PhD Students Only

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4-year PhD Studentship: Combatting bacterial zoonoses through multi-disciplinary studies of virulence factors

University of Bristol Bristol Veterinary School

Vector-borne diseases, including bacterial zoonoses, pose a significant threat to human and animal health and to livestock industries, particularly in low and middle-income countries. Read more

Supervisor: Dr T Cogan

Year round applications PhD Research Project Self-Funded PhD Students Only

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The Survivin Interactome in Health and Disease

University of Nottingham School of Life Sciences

Survivin is a small protein that is essential for life but that also contributes to disease, most notably cancer, in which its abnormal overexpression is linked to therapeutic resistance and metastasis. Read more

Supervisor: Dr S Wheatley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

Supervisors: Dr H O'Hare, Dr N Garton

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders

University of Leeds Faculty of Biological Sciences

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Prof I Wood

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Deciphering the ubiquitin codes that regulate protein degradation

University of Dundee School of Life Sciences

Ubiquitin signalling, which involves the posttranslational modification (PTM) of proteins with ubiquitin, regulates almost every aspect of eukaryotic biology. Read more

Supervisor: Prof Y Kulathu

Year round applications PhD Research Project Self-Funded PhD Students Only

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