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We have 35 Molecular Biology (regulatory) PhD Projects, Programmes & Scholarships

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Molecular Biology (regulatory) PhD Projects, Programmes & Scholarships

We have 35 Molecular Biology (regulatory) PhD Projects, Programmes & Scholarships

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Delineating the IRF6 regulatory network driving periderm formation and function

The University of Manchester Faculty of Biology, Medicine and Health
During development, the ectoderm passes through a series of cell states to produce a self-replenishing, multi-layered epidermis. Initial stratification forms a single-cell layer of flattened periderm cells which act as a barrier to prevent pathological adhesions during embryogenesis. Read more
 Supervisors: Prof M Dixon, Dr J Dixon
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of regulatory evolution in phage ecology

The University of Manchester Faculty of Biology, Medicine and Health
The regulation of genes crucially determines the fitness and function of all organisms. This is particularly relevant for bacteriophages, the viruses that infect bacteria, as they rely on a tightly scheduled program for a successful infection. Read more
 Supervisors: Dr M Lagator, Dr CI Igler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self-funded PhD in Biology: Engineering Gene Regulatory Networks To Enhance Crop Disease Resistance

University of York Department of Biology
Lead supervisor: Prof K Denby . Co-Supervisor: Dr B R Lichman. The student will be registered with the Department of Biology. Read more
 Supervisors: Prof K Denby, Dr B R Lichman
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The University of Manchester Faculty of Biology, Medicine and Health
The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more
 Supervisors: Dr MM Mennon, Prof MH Buch
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Regulation of virulence and biofilm formation by quorum sensing and the "stress alarmone" ppGpp in gram-negative pathogenic bacteria.

University of Cambridge Department of Biochemistry
We are investigating the complex interplay between cell-cell signalling (quorum sensing), microbial lifestyle (i.e., free-living planktonic cultures vs sessile biofilm communities), growth phase and virulence in gram-negative bacteria. Read more
 Supervisor: Dr M Welch
 Year round applications  PhD Research Project  Awaiting Funding Decision/Possible External Funding
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Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies

University of Leicester Molecular and Cell Biology
Whether a cell dies or not has profound consequences on health and disease. In healthy tissue, cells that acquire high levels of genetic damage are safely removed via a process of programmed cell death. Read more
 Supervisor: Dr JF Fox
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The genetic map of human molecular phenotypes

University of Bristol Bristol Medical School
Rationale. Genome wide associations studies (GWASs) have discovered many genetic associations with a large range of human traits, but the functional consequences of GWAS signals often remain elusive, as most GWAS signals reside in non-coding genomic regions. Read more
 Supervisors: Dr J Min, Dr G Hemani, Dr JH Hawe
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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PhD studentship - Defining the mechanisms underpinning HIF-1 and HIF-2 dependent transcriptional specificity in hypoxia.

Newcastle University Biosciences Institute
Award summary. 100% of home tuition fees paid and annual living expenses of £18,622. Overview. The cellular response to low oxygen levels (hypoxia), is crucial for cell survival and identity. Read more
 Supervisor: Dr B Ortmann
 14 June 2024  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Development of novel therapies for Hirschsprung’s Disease

University of Liverpool Faculty of Health and Life Science
As a PhD student, you'll be part of a groundbreaking project aiming to revolutionise the treatment landscape for Hirschsprung's Disease (HSCR). Read more
 Supervisors: Miss RH Harwood, Dr B Wilm, Miss SA Almond
 26 April 2024  PhD Research Project  Funded PhD Project (European/UK Students Only)
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PhD candidate - Origin of Obesity and Metabolic Disorders in Childhood (f/m/x)

Helmholtz Zentrum Munich Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG)
We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. Read more
 Supervisor: Prof S Körner
 22 March 2025  PhD Research Project  Funded PhD Project (Students Worldwide)
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Bidirectional mobile sRNA signalling in pea-downy mildew interactions

University of Worcester Research School
Plants are constantly being challenged by microbial pathogens and they have evolved the capacity to detect and defend against these incoming microbes. Read more
 Supervisor: Prof M Tor
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Chromatin regulation of oncogenic transcription and replication stress: mechanism and functional implications in acute myeloid leukemia

University of Liverpool Institute of Systems, Molecular and Integrative Biology
This project focuses on the molecular mechanisms promoting acute myeloid leukaemia (AML), a disease of great unmet need. AML is an aggressive blood and bone marrow cancer characterized by abnormal proliferation and differentiation of myeloid cells. Read more
 Supervisors: Dr M Papamichos Chronakis, Prof D MacEwan, Dr A Kanhere
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developmental consequences of heat stress during early mammalian embryogenesis

University of Nottingham School of Biosciences
Epidemiological evidence in humans indicates that acute heat exposure around the time of mating results in pregnancy loss, with potential long-term consequences for offspring health and wellbeing; although these latter adverse effects are poorly understood. Read more
 Supervisors: Prof K D Sinclair, Dr R Alberio, Prof D Gardner
 10 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Identifying variants impacting splicing of 5’ and 3’ UTRs and underpinning inherited retinal disease

The University of Manchester Faculty of Biology, Medicine and Health
Genomic variation that impacts splicing is well established as a cause of genomic disorders, but is almost exclusively limited to protein-coding exons and introns intersecting protein-coding exons. Read more
 Supervisors: Dr J Ellingford, Prof R O'Keefe
 15 June 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences
Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more
 Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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