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We have 7 Molecular Biology (sclerosis) PhD Projects, Programmes & Scholarships

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Molecular Biology (sclerosis) PhD Projects, Programmes & Scholarships

We have 7 Molecular Biology (sclerosis) PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

NIHR Leeds BRC: An interferon diagnostic to inform early detection and prevention strategies in Ana positive CTDs

Type I interferons (IFN) play a role in a wide range of rheumatic and musculoskeletal diseases (RMDs), and strong evidence suggests that measurement of IFN activity could have clinical value, although testing has not progressed into clinical settings. Read more

Stress hormone metabolism – a novel anti-fibrotic therapeutic pathway for chronic wounds (Ref SHLS24121)

We have an exciting PhD opportunity within the Molecular Mechanisms of Long-term Conditions research group at Glasgow Caledonian University (https://www.gcu.ac.uk/aboutgcu/academicschools/hls/research/researchgroups/molecularmechanismsoflongtermconditions) to join the laboratory of Dr Catherine Wright with a supervisory team based in GCU and the University of Leeds. Read more

The Survivin Interactome in Health and Disease

Survivin is a small protein that is essential for life but that also contributes to disease, most notably cancer, in which its abnormal overexpression is linked to therapeutic resistance and metastasis. Read more

Targeting ageing and neurodegenerative diseases using the fruit-fly Drosophila melanogaster

In the last 20 years the fruit fly Drosophila melanogaster emerged as a pre-eminent model system for studying changes that occur during both normal and pathological ageing (~75 per cent of the genes that cause disease in humans are also found in the fruit fly!). Read more
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