Molecular Biology (t cells) PhD Projects, Programmes & Scholarships

We have 20 Molecular Biology (t cells) PhD Projects, Programmes & Scholarships

Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences

Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more

Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

University of Dundee School of Life Sciences

T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more

Supervisor: Dr T Ly

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Protein secretion landscapes in human immune cells

University of Dundee School of Life Sciences

Roughly one third of the human genome encodes secretory and membrane proteins. Following synthesis in the endoplasmic reticulum (ER), these proteins are captured into transport vesicles for delivery within the cell. Read more

Supervisors: Dr L Miller, Dr A Howden

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

The University of Manchester Faculty of Biology, Medicine and Health

Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more

Supervisors: Dr S Nagarajan, Dr HH Harrison, Prof R Clarke, Dr I Iqbal

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Evaluating the role of immune microenvironment on cancer progression using spatial and imaging approaches

King’s College London School of Cancer and Pharmaceutical Sciences

Talented and motivated students, passionate about doing research and advancing cancer research, are invited to apply for this PhD position. Read more

Supervisor: Dr H Sailem

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Supervisors: Dr F Errington-Mais, Dr V Jennings

Year round applications PhD Research Project Self-Funded PhD Students Only

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Non-invasive Therapy for Soft Tissue Reconstruction: Applications in Cosmetics and Wound Healing

Newcastle University Faculty of Medical Sciences Graduate School

Soft tissue reconstruction is emerging as an important strategy to repair and replace diseased or damaged tissue that has been compromised due to tumour removal, injury, trauma, ageing, etc. Read more

Supervisors: Dr K Wooi Ng, Dr O Almusaimi

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

The University of Manchester Faculty of Biology, Medicine and Health

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Supervisors: Prof D Brough, Dr K Couper

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies

University of Leicester Molecular and Cell Biology

Whether a cell dies or not has profound consequences on health and disease. In healthy tissue, cells that acquire high levels of genetic damage are safely removed via a process of programmed cell death. Read more

Supervisor: Dr JF Fox

Year round applications PhD Research Project Self-Funded PhD Students Only

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Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology

Ever wondered how nature maintains balance of gene expression between sex chromosomes? Well, the 46th chromosome of XX females, the second X, has to be switched off. Read more

Supervisors: Dr Y Markaki, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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MSc by Research: m6A modification of segmentation clock mRNAs and its role in somitogenesis

University of Dundee School of Life Sciences

During early embryogenesis, segments (somites) are formed during a process called somitogenesis. These somites will go on to form the bones and muscles of the skeleton. Read more

Supervisors: Prof J K Dale, Dr P Murray

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanisms underlying the anti-atherogenic actions of natural products

Cardiff University Cardiff School of Biosciences

Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for most deaths in the western world with mortality increasing at a marked rate in developing. Read more

Supervisors: Dr D Ramji, Dr T Hughes

Year round applications PhD Research Project Self-Funded PhD Students Only

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NIHR Leeds BRC: Pre-clinical evaluation of novel regenerative medicine strategies for knee osteoarthritis

University of Leeds Faculty of Medicine and Health

Historically, articular cartilage was considered incapable of spontaneous repair. However, biomechanical correction in osteoarthritis (OA) using high tibial osteotomy or joint distraction demonstrated the remarkable joint to regeneration by “merely” correcting joint alignment. Read more

Supervisors: Prof H Pandit, Prof D McGonagle

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigating lysosomal (dys)function in ageing and neurodegeneration

University of Reading Department of Biomedical Sciences

Project Overview. Ageing is associated with a decline in the functions of an organism (López-Otín, C. et al. Cell, 2023) and correlates with an increased risk of developing diseases in the later life (Niccoli, T. Read more

Supervisors: Dr S Cogo, Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

University of Leicester Molecular and Cell Biology

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

Supervisor: Dr G Hall

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 20 Molecular Biology (t cells) PhD Projects, Programmes & Scholarships

Molecular Biology (t cells) PhD Projects, Programmes & Scholarships

We have 20 Molecular Biology (t cells) PhD Projects, Programmes & Scholarships

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