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We have 31 Epidemiology (genetic epidemiology) PhD Projects, Programmes & Scholarships

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Epidemiology (genetic epidemiology) PhD Projects, Programmes & Scholarships

We have 31 Epidemiology (genetic epidemiology) PhD Projects, Programmes & Scholarships

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Using nutrigenetic, nutrigenomic and machine learning approaches to investigate the risk of cardiometabolic disease-related traits in ethnically diverse populations.

University of Reading Department of Food and Nutritional Sciences
This PhD project represents an exciting opportunity to develop and conduct research at the forefront of nutritional and genetic epidemiology, contributing to the prediction, prevention, and better understanding of the development of non-communicable diseases such as obesity and diabetes, using datasets from multiple ethnic groups. Read more
 Supervisor: Dr V Karani
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding psychiatric outcomes in children born with cleft lip and/or palate using genetics

University of Bristol Bristol Medical School
Rationale. Cleft of the lip and/or palate is a common birth defect worldwide and occurs at a rate of one in 650 live births in the UK. Read more
 Supervisors: Dr E Stergiakouli, Dr S Lewis, Prof M J Owen, Dr M van den Bree
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Evaluating the role of circulating proteins in cancer risk and progression using genetic and observational approaches

University of Bristol Bristol Medical School
Rationale. Circulating proteins play fundamental roles in biology and disease aetiology, including development of cancer, and are the direct targets of many drugs (1). Read more
 Supervisors: Prof R Martin, Dr JY Yarmolinsky, Dr P Haycock
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Investigating the role of dietary fructose in the development of early-onset colorectal cancer

University of Bristol Bristol Medical School
Project Background. This project will investigate the role of fructose in the development of early-onset colorectal cancer (EOCRC) in adults <50 years. Read more
 Supervisors: Dr E Vincent, Dr A Chambers, Dr R Richmond, Dr NM Murphy
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Integrative genomics prioritisation of drug targets

University of Bristol Bristol Medical School
The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more
 Supervisor: Prof T Gaunt
 20 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School
The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more
 Supervisor: Prof T Gaunt
 20 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School
Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more
 Supervisors: Dr J Min, Dr E Hannon, Prof J MIll, Dr GL Leyden
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Establishing and orienting causal relationships between sleep characteristics and reproductive function

University of Bristol Bristol Medical School
Rationale. A large body of literature from animal studies has highlighted the role of core clock genes in relation to reproductive function [1]. Read more
 Supervisors: Dr R Richmond, Dr G Sharp, Prof D Lawlor
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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The genetic map of human molecular phenotypes

University of Bristol Bristol Medical School
Rationale. Genome wide associations studies (GWASs) have discovered many genetic associations with a large range of human traits, but the functional consequences of GWAS signals often remain elusive, as most GWAS signals reside in non-coding genomic regions. Read more
 Supervisors: Dr J Min, Dr G Hemani, Dr JH Hawe
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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An investigation of the causal relationship and genetic overlap between sleep traits and physical and mental health using Mendelian randomization

University of Bristol Bristol Medical School
Rationale. Sleep has long been known to play a role in physical and mental wellbeing and sleep disruption has been observed to co-occur with a number of health conditions including. Read more
 Supervisors: Dr S Lewis, Dr MR Renteria, Dr HJ Jones
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Metabolomic characterisation of adiposity across the life course

University of Bristol Bristol Medical School
There is evidence that adiposity, measured by body mass index (BMI), causally influences a range of health outcomes, but little understanding of the mechanisms driving BMI effects. Read more
 Supervisor: Dr L Corbin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Harnessing genetics of DNA methylation to elucidate molecular mechanisms underlying human phenotypes.

University of Bristol Bristol Medical School
Rationale. GWAS studies have discovered many genetic associations for traits and diseases, but it has been difficult to elucidate the functional consequences of these variants. Read more
 Supervisors: Dr J Min, Prof C Relton, Prof J MIll, Dr E Hannon, Dr G Hemani, Prof T Gaunt, Dr B Heijmans, Dr J Bell
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Linking multivariable Mendelian randomization with lifecourse epidemiology: developing the methodology and application to a contemporary exemplar

University of Bristol Bristol Medical School
Rationale. Mendelian randomization (MR) uses genetic variants as instrumental variables to estimate the causal effect of an exposure on an outcome, free from bias due to unobserved confounding. Read more
 Supervisors: Dr E Sanderson, Prof K Tilling, Prof G Davey-Smith
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Identifying causal pathways to disease using DNA methylation derived scores.

University of Bristol Bristol Medical School
Rationale. DNA methylation is an epigenetic biomarker that has been shown to reflect lifestyle and biological factors (smoking, alcohol use, chronological age). Read more
 Supervisors: Dr J Min, Prof C Relton, Prof J MIll, Dr E Hannon, Dr G Hemani, Prof T Gaunt, Dr B Heijmans, Dr J Bell
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Early life factors in the development of Juvenile idiopathic arthritis

The University of Manchester Faculty of Biology, Medicine and Health
Juvenile idiopathic arthritis (JIA) is an autoimmune inflammatory arthritis with disease onset before the age of 16. Children and young people with this condition develop painful swollen joints and untreated it can lead to long term disability. It may also be associated with comorbid conditions such as uveitis. Read more
 Supervisors: Dr J Humphreys, Dr J Bowes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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